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PedAM

Pediatric Disease Annotations & Medicines




Disease osteoporosis
Phenotype C0024141|systemic lupus erythematosus
Sentences 2
PubMedID- 22897816 osteoporosis in patients with systemic lupus erythematosus (sle) is thought to be the result of accelerated osteoclastogenesis induced by pro-inflammatory cytokines such as tumor necrosis factor (tnf).
PubMedID- 26445510 (2015) reveal that the ability of transplanted mscs to alleviate osteoporosis in systemic lupus erythematosus is maintained through epigenetic changes conferred by secretory action of the mscs.

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