PedAM
Pediatric Disease Annotations & Medicines
| Disease | osteoporosis |
| Phenotype | C0022661|chronic renal failure |
| Sentences | 1 |
| PubMedID- 21403406 | The diagnosis of osteoporosis in chronic renal failure is not easy to make due to the confounding effects of renal osteodystrophy and superimposed osteomalacia that may also result in fractures and low bmd.75 in stage 1 through 3 chronic kidney disease (ckd), the metabolic changes that accompany early ckd are intermittent hyperphosphotemia and a mild increase of parathyroid hormone.77 fractures in stage 1 through 3 ckd are most likely caused by osteoporosis than ckd-related metabolic bone disease.76 who criteria or low trauma fractures for diagnosis of osteoporosis in stage 1 through 3 ckd can be used once other metabolic and biochemical abnormalities have been corrected.76 the current fda recommendation is to avoid oral bisphosphonates in patients with glomerular filtration rates (gfr) below 35 ml/minute. |
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