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PedAM

Pediatric Disease Annotations & Medicines




Disease osteoporosis
Phenotype C0011854|type 1 diabetes
Sentences 4
PubMedID- 21395677 Aim: there are conflicting data regarding the risk of osteoporosis in patients with type 1 diabetes.
PubMedID- 24721668 Our study shows a similar risk of osteoporosis in patients with type 1 diabetes based on low bmd (t-score < −2.5 sd), which was not different from the prevalence in patients with type 2 diabetes despite them being approximately 20 years older.
PubMedID- 26135835 type 1 diabetes (t1d)-induced osteoporosis is characterized by a predominant suppression of osteoblast number and activity, as well as increased bone marrow adiposity but no change in osteoclast activity.
PubMedID- 24348809 Insulin deficiency accelerates bone loss and is potentially the main cause of osteoporosis in patients with type 1 diabetes mellitus (15).

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