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PedAM

Pediatric Disease Annotations & Medicines




Disease optic neuritis
Phenotype C0456909|blindness
Sentences 5
PubMedID- 26133362 This article reports the first known case of permanent blindness due to irreversible unilateral optic neuritis (on) related to infliximab (remicade) treatment of a patient with ulcerative colitis.
PubMedID- 19941048 The disease can produce a wide variety of symptoms, including impaired motor function or feeling in limbs, debilitating fatigue, pain, loss of bowel or bladder control, sexual dysfunction, blindness due to optic neuritis, impaired cognitive functioning and emotional symptoms (goodkin 1992; mohr and cox 2001).
PubMedID- 22946013 Corticosteroids are widely used in medicine and they have saved lives, prevented blindness from the result of optic neuritis and revolutionized the management of autoimmune disease but they have brought their own complications and are considered as a risk factor for osteoporosis [13].
PubMedID- 23575266 In more than 90% of cases, nmo is a relapsing disease with severe cumulative disabilities including paraplegia and blindness due to optic neuritis.
PubMedID- 21465340 Ocular changes may also develop a few weeks after disease onset: anterior uveitis, retinitis, episcleritis, and optic neuritis, sometimes leading to blindness [42].

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