PedAM
Pediatric Disease Annotations & Medicines
| Disease | obstructive jaundice |
| Phenotype | C0031154|peritonitis |
| Sentences | 2 |
| PubMedID- 20383819 | Clinical course of obstructive jaundice associated with operated meconium peritonitis in neonates. |
| PubMedID- 21415977 | obstructive jaundice),62,72,73 and in patients with peritonitis (in peritoneal macrophages) or acute respiratory distress syndrome (in broncho-alveolar lavage, bal, fluid).62,74 interestingly, in some studies, monocyte tf was related with blood clotting activation, severe organ dysfunction and lethal outcome.62,72,73 surprisingly, and in contrast with the abundant in vitro evidence, ecs were negative for tf in most animal studies,61,63,65,67 with few exceptions.64,75,76 in one study tf expression was found in ecs within the splenic microvasculature of septic baboons but not in ecs of pulmonary vessels.64 others observed the expression of tf activity on intact aortic ecs of endotoxin-treated rabbits.75 more recently, lupu et al.76 observed tf protein and activity especially on ecs at branch points of the aorta of septic baboons and suggested that site-dependent endothelial heterogeneity coupled with rheological factors might influence the focal vascular procoagulant response to sepsis. |
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