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PedAM

Pediatric Disease Annotations & Medicines




Disease neutropenia
Phenotype C0020538|hypertension
Sentences 5
PubMedID- 22633505 In premature infants, early-onset neutropenia is correlated with sepsis, maternal hypertension, intrauterine growth restriction, severe asphyxia, and periventricular haemorrhage, and might be associated with an increase in the incidence of early-onset sepsis, nosocomial infection, and candida colonisation.
PubMedID- 20799326 We propose that dursun syndrome should now be considered as a subset of severe congenital neutropenia type 4 with pulmonary hypertension as an important clinical feature.
PubMedID- 20046507 The rate of ≥ grade 3 hypertension, vomiting, neutropenia, bleeding, and proteinuria were modestly higher in the bevacizumab arms than in the placebo arm.
PubMedID- 23420139 While in some patients the disease remained static, in a larger proportion a more severe disease developed characterized by portal hypertension, the latter leading to hypersplenism with neutropenia and thrombocytopenia and, in some cases, to ascites.
PubMedID- 24816725 Grade 3/4 treatment-emergent adverse events observed in the mgn1703 group included ileus (n = 4), hypertension (n = 2), worsening of hypertension (n = 2), neutropenia, aspartate aminotransferase increase, sensory polyneuropathy and sepsis (each n = 1).

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