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PedAM

Pediatric Disease Annotations & Medicines




Disease neutropenia
Phenotype C0019158|hepatitis
Sentences 7
PubMedID- 24257097 Purpose of review: this review describes the pathogenesis and therapeutic implications of neutropenia in patients with hepatitis c.
PubMedID- 24675038 Feasibility of pegylated interferon and ribavirin in hepatitis c-related cirrhosis with neutropenia or thrombocytopenia.
PubMedID- 20731132 [clinical significance of leukopenia and neutropenia patients with chronic hepatitis "c" in the various regimes antiretroviral therapy].
PubMedID- 23171914 Severe neutropenia in patients with chronic hepatitis c: a benign condition.
PubMedID- PMC4034027 Recent reports suggest that certain polymorphisms in type i ifn signaling molecules are associated with ifn-induced neutropenia and thrombocytopenia in patients with chronic hepatitis c. ifnγ binds to a cell-surface receptor composed of two transmembrane polypeptides ifgr1 and ifgr2 resulting in activation of the janus kinases jak1 and jak2, phosphorylation of stat1, formation of stat1 homodimers, and activation of a specific set of genes that encode the effector molecules responsible for mediating its biological activity.
PubMedID- 21415945 The implications of these data for interferon-related neutropenia in patients with chronic hepatitis c are not wholly clear.
PubMedID- 20361278 Therapy was directed at the underlying hepatitis with resolution of neutropenia without the use of colony-stimulating factors.

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