PedAM
Pediatric Disease Annotations & Medicines
| Disease | neutropenia |
| Phenotype | C0007113|rectal cancer |
| Sentences | 5 |
| PubMedID- 22740978 | Correlation between plasma concentration ratios of sn-38 glucuronide and sn-38 and neutropenia induction in patients with colorectal cancer and wild-type ugt1a1 gene. |
| PubMedID- 25880011 | Clinically, this internally and externally validated nomogram will most likely be useful for predicting the probability of irinotecan-induced severe neutropenia in patients with colorectal cancer. |
| PubMedID- 25981652 | [examination of ugt1a1 polymorphisms and irinotecan-induced neutropenia in patients with colorectal cancer]. |
| PubMedID- 24932285 | However, the 421c>a variant is not associated with cpt-11-induced severe neutropenia in patients with lung and colorectal cancer (8,21). |
| PubMedID- 26370544 | Compared with the japanese randomized phase 2 trial in patients with colorectal cancer, rates of grade 3/4 neutropenia (71 vs. 50 %), febrile neutropenia (8 vs. 4 %), and anemia (25 vs. 17 %) were modestly increased among western patients, though these findings may be due to the sample size differences between the two trials. |
Page: 1