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PedAM

Pediatric Disease Annotations & Medicines




Disease neutropenia
Phenotype C0002871|anemia
Sentences 13
PubMedID- 23826577 In general, treatment with a hypomethylating agent is recommended for patients with thrombocytopenia or neutropenia or in patients with anemia who are unresponsive to other therapies [1].
PubMedID- 21998605 Peripheral blood smear showed normochromic normocytic anemia with anisopoikilocytosis 2+, neutropenia, lymphocytopenia, relative monocytosis 14%, and thrombocytopenia.
PubMedID- 22162923 Adverse side effects included grade ≥3 anemia (13% of patients) and neutropenia (50% of patients).
PubMedID- 21367725 Background: persistent neutropenia associated with severe aplastic anemia (saa) is an important risk factor for development of life-threatening infections.
PubMedID- 25853131 Cytopenia include anemia (adeficiency of rbcs), leukopenia or neutropenia (a deficiency of wbcs or leukocytes), thrombocytopenia (a deficiency of platelets), and pancytopenia (a deficiency of all three blood cell types—rbc, wbc, and platelet) (smith, 2010).
PubMedID- 24833969 [40] found a non-regenerative anemia, with neutropenia, thrombocytopenia and normallymphocyte count.
PubMedID- 26279668 Unexplained anemia defined as hemoglobin of less than 8 g/dl, neutropenia <1000 cells/mm3 or thrombocytopenia less than 30,000 platelets/mm3 persisting for more than one month are currently classified as who stage 3 disease [2].
PubMedID- 21772952 Evans syndrome (es) is an autoimmune disorder characterized by thrombocytopenia and/or neutropenia associated with hemolytic anemia (aha).1–3 it is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymph-proliferative disorders.4 standard treatment consists of transfusions, corticosteroids and immunoglobulins (ivig); second-line treatment in es evolved over the last decade, and includes at present anti-cd20 rituximab, vincristine, alkalizing agents, mycophenolate mofetil (mmf) or cyclosporine (cya).5–6,8–14 long-term remissions induced by splenectomy are less frequent than in uncomplicated immune thrombocytopenia purpura (itp).
PubMedID- 24505539 Regarding, chemotherapy-related complications in the first group, two patients had anemia, two of them had neutropenia, one had thrombocytopenia, and another one skin lesions.
PubMedID- 25867940 Hematologic abnormalities included moderate nonregenerative anemia, leucopenia with neutropenia, and moderate thrombocytopenia.
PubMedID- 21597288 Grade 3 and 4 toxicities included anemia (20.5% of patients), thrombocytopenia (2.3%), neutropenia (10.3%), aspartate transaminase increase (10.3%), alanine transaminase increase (5.1%) and emesis (5.1%).
PubMedID- 24555093 Laboratory tests upon admission showed severe neutropenia with moderate anemia and thrombocytopenia, increased prothrombin time (pt), partial thromboplastin time (ptt) and low fibrinogen (table 2).
PubMedID- 23056691 In our patient the main manifestations were neurological features (seizures, developmental regression, brain atrophy), and hematologic (macrocytic sideroblastic anemia, vacuolization of hematopoietic precursors and neutropenia).

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