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PedAM

Pediatric Disease Annotations & Medicines




Disease neuropathy
Phenotype C0035309|retinopathy
Sentences 18
PubMedID- 23066426 Microvascular complications included retinopathy (16.2% of all patients), neuropathy (11.2%), nephropathy (1.5%) and combination of neuropathy and retinopathy (6.5%).
PubMedID- 24809393 Recent data revealed that early retinal neuropathy in patients with diabetic retinopathy involved a reduced expression of brain-derived neurotrophic factor.
PubMedID- 23198007 The results of this study suggest that mfvep could be an indicator of neurodegenerative influence on bipolar cells and of optic nerve neuropathy in patients with diabetic retinopathy and that there is a correlation between this dysfunction and diabetic neuropathy.
PubMedID- 21977459 [16] showed that diabetic neuropathy was associated with retinopathy in type 2 diabetes mellitus.
PubMedID- 21273496 Age, sex, age at diabetes diagnosis, diabetes duration, hba1c levels, hypertension status, proteinuria, bmi, smoking status, heavy smoking, retinopathy severity, and history of cardiovascular disease and neuropathy at baseline were considered potential risk factors.
PubMedID- 22988507 Furthermore, t2dm is most common in older adults, who as a result of this disease often experience various comorbidities [49], further reducing their capacity to live independently (e.g., retinopathy, which may lead to blindness; peripheral neuropathy, which may lead to foot ulcers and amputations; nephropathy, which over time could result in renal failure, etc.).
PubMedID- 25143913 In cases having two microvascular complications the mean duration of diabetes was 4.3 ± 1.34 years (neuropathy with retinopathy), 4.63 ± 2.9 years (neuropathy with nephropathy) and 5.33 ± 3.24 years (retinopathy with nephropathy).
PubMedID- 24455698 Exclusion criteria were as follows: presence of cardiac arrhythmia, heart block, clinical coronary artery disease, presence of thyroid disease (hypo- or hyperthyroidism), presence of hypo- or hyperglycaemia in the previous 24 h, presence of acute illness, severe systemic disease such as cardiac, pulmonary, or kidney insufficiency, medication that affects the autonomic nervous system (antiarrhythmic medication, antidepressants, antihistamine, and sympathomimetic cough preparations), advanced diabetic retinopathy, other obvious causes of neuropathy, for example, alcohol abuse, use of neurotoxic medication or malignant disease, history of diabetic ketoacidosis, and other secondary causes of diabetes [1].
PubMedID- 24627251 Independent primary retinopathy in the setting of known optic neuropathy can also coexist, and patients with retinopathy can also develop optic neuropathy.
PubMedID- 21523218 The chronic hyperglycemia associated with diabetes leads to long-term complications including cvd, nephropathy leading to renal failure, retinopathy with potential loss of vision, and peripheral neuropathy (27).
PubMedID- 21744285 Our research identified new aabs specific against optic nerve antigens not previously known in autoimmune neuropathy associated with retinopathy, suggesting the autoimmune nature of the syndrome also at the optic nerve level.
PubMedID- 23846809 Interestingly, nse was shown to be more elevated in neuropathy with retinopathy than without in our study.
PubMedID- 25995810 Severe hypertensive retinopathy with optic neuropathy may be a consequence of malignant hypertension due to a pheochromocytoma.
PubMedID- 26341632 Similarly, the associations between glucosepane and retinopathy, and mg-h1 with neuropathy were not nullified by adjustment for dcct a1c, respectively.
PubMedID- 23193205 In contrast, gender distribution, 24-h sbp, dbp, map, albuminuria group, uaer, hba1c, total cholesterol, smoking status, retinopathy status, and prevalence of autonomic neuropathy were similar among participants with and without pwv measurements (p > 0.05 for all).
PubMedID- 25699225 Nephropathy leading to renal failure; retinopathy with loss of vision; peripheral neuropathy with risk of foot ulcers and amputations are long-term complications of diabetes [1].
PubMedID- 23217385 Hba1c, hyperlipidemia, and retinopathy were significantly associated with neuropathy, and these risk factors were correlated with other diabetic micro and/or macrovascular complications.
PubMedID- 21470000 The complication status involved retinopathy (62% of patients), neuropathy (34.6%), nephropathy (26%), and cardiovascular disease (14%).

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