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PedAM

Pediatric Disease Annotations & Medicines




Disease neuropathy
Phenotype C0026470|monoclonal gammopathy of undetermined significance
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PubMedID- 23525653 Early treatment with rituximab may also be effective in patients with anti-mag/sgpg neuropathy associated with monoclonal gammopathy of undetermined significance.
PubMedID- 20940626 To characterize the morphological progression of neuropathy associated with immunoglobulin m-monoclonal gammopathy of undetermined significance with anti-myelin-associated glycoprotein antibody, we assessed histopathologic features of sural nerve specimens from 15 patients, emphasizing widely spaced myelin (wsm), demyelination, and tomaculous changes.
PubMedID- 22189568 In the remaining cohorts (monoclonal gammopathy of undetermined significance related polyneuropathy, multifocal motor neuropathy, mytonic dystrophy type-1, pompe's disease and limb-girdle muscular dystrophy), the muscles groups evaluated represented the clinical picture of each illness (see supplementary table 1 for available muscles per cohort).

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