PedAM
Pediatric Disease Annotations & Medicines
| Disease | neuropathy |
| Phenotype | C0011854|type 1 diabetes |
| Sentences | 38 |
| PubMedID- 23882058 | These data thus suggested that glucose variability may be important in the development of peripheral neuropathy in patients with type 1 diabetes and that the nervous system may be particularly vulnerable to glycemic variability (9). |
| PubMedID- 23391743 | The evaluation of peripheral neuropathy in youth with type 1 diabetes. |
| PubMedID- 25406279 | Natural history of corneal nerve morphology in mild neuropathy associated with type 1 diabetes: development of a potential measure of diabetic peripheral neuropathy. |
| PubMedID- 21911773 | There are no studies examining neuropathy in patients with type 1 diabetes and cd or the effect of a gfd. |
| PubMedID- 25139473 | To date, tight glycemic control is the only strategy convincingly shown to prevent or delay the development of neuropathy in patients with type 1 diabetes and to slow the progression of neuropathy in some patients with type 2 diabetes. |
| PubMedID- 21256797 | Nonlinear pd2i heart rate complexity algorithm detects autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 25853247 | In this cross-sectional, observational study we aimed to assess whether neuropathy occurred in patients with type 1 diabetes, without retinopathy or microalbuminuria. |
| PubMedID- 20040675 | The absence of similar small-fiber neuropathy in those with longstanding type 1 diabetes suggests that glycemia may not be the major determinant of small-fiber neuropathy in igt. |
| PubMedID- 22934084 | Autonomic neuropathy in type 1 diabetes has been suggested to cause hyper-reactivity to nitro vasodilators in the forearm vasculature (mäkimattila et al., 1997). |
| PubMedID- 21466989 | Natural progression of cardiac autonomic neuropathy in patients with type 1 diabetes: a four-year follow-up study. |
| PubMedID- 23193205 | Arterial stiffness also is associated with autonomic neuropathy in type 1 diabetes (22,23) and retinopathy in type 2 diabetes (24), further illustrating the association between arterial stiffness and microvascular disease. |
| PubMedID- 25251450 | Conclusion: this study suggests that corneal confocal microscopy could represent a new and non-invasive tool to investigate cardiac autonomic neuropathy in people with type 1 diabetes. |
| PubMedID- 24651803 | It has been demonstrated that 1-deoxysls are cytotoxic in various model systems, and more important, they are implicated in the pathology of neuronal functional impairment in hereditary sensory and autonomic neuropathy in patients with type 1 diabetes (hsan1) (10). |
| PubMedID- 21892113 | Wolfram syndrome: a rare optic neuropathy in youth with type 1 diabetes. |
| PubMedID- 24803311 | Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease [corrected]. |
| PubMedID- 25505446 | Predictors of cardiovascular autonomic neuropathy in patients with type 1 diabetes. |
| PubMedID- 20464532 | The dcct/edic (diabetes control and complications trial/ epidemiology of diabetes interventions and complications) provides a comprehensive characterization of the natural history of diabetic neuropathy in patients with type 1 diabetes and provides insight into the impact of intensive insulin therapy in disease progression. |
| PubMedID- 24846202 | Auditory neuropathy in individuals with type 1 diabetes. |
| PubMedID- 23723354 | Objective: the aim of this study was to elucidate whether subclinical nerve dysfunction as reflected by neurophysiological testing predicts the development of clinical neuropathy in patients with type 1 diabetes. |
| PubMedID- 23641349 | Thus, treatment with c-peptide can slow the progression of neuropathy in patients with type 1 diabetes [13]. |
| PubMedID- 25783659 | However, adequate data is not available to determine whether regular exercise would prevent or delay the development of painful neuropathy in subjects with type 1 diabetes. |
| PubMedID- 26241393 | Purpose: we investigated the relationship between corneal subbasal nerve (sbn) plexus density, corneal sensitivity, and peripheral and cardiac autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 25981398 | Conclusion: these data suggest that cpt is useful in early detection of peripheral neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 22892951 | Purpose of review: to compare and contrast the evidence for the effect of glucose control on the prevention of neuropathy in type 1 diabetes mellitus (t1dm) and type 2 diabetes mellitus (t2dm). |
| PubMedID- 20833868 | Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the dcct/edic study. |
| PubMedID- 22030241 | Haemodynamic changes during a squat test, pulsatile stress and indices of cardiovascular autonomic neuropathy in patients with long-duration type 1 diabetes. |
| PubMedID- 21819228 | Pulse wave analysis and cardiac autonomic neuropathy in type 1 diabetes: a report from the pittsburgh epidemiology of diabetes complications study. |
| PubMedID- 24550215 | Objective we prospectively evaluated the association between autoimmunity to autonomic nervous structures and autonomic neuropathy in type 1 diabetes in relation to clinical variables. |
| PubMedID- 26207222 | In both type one and two diabetic patients, results of the clinical investigations three years after the procedure clearly revealed that there were no significant differences in the incidence or progression of diabetes micro vascular complications in patients who had either undergone fetal liver-derived cell suspension allotransplantation or received placebo compared to the baseline (table 2).table 2presence of retinopathy,neuropathy and microalbuminuria in patients with type 1 diabetes at the baseline and 3 years following the interventiontype 1 diabetesretinopathy (baseline)totalp-valuerethinopathy (3rd year)totalp-valuenormalpdrnormalnpdrgroupsinterventioncount130130.999b111120.999b(%)100.0%.0%100.0%91.7%8.3%100.0%placebocount1611712012(%)94.1%5.9%100.0%100.0%.0%100.0%totalcount2913023124(%)96.7%3.3%100.0%95.8%4.2%100.0%neuropathy (basal)totalp-valueneuropathy (3rd year)totalp-valueno_neurophathyneuropathy+no_neurophathyneuropathy+groupsinterventioncount121130.433b102120.478b(%)92.3%7.7%100.0%83.3%16.7%100.0%placebocount1701712012(%)100.0%.0%100.0%100.0%.0%100.0%totalcount2913022224(%)96.7%3.3%100.0%91.7%8.3%100.0%microalbominuria (baseline)totalp-valuemicroalbominuria (3rd year)totalp-valueno albominuriamicroalbominuria+no albominuriamicroalbominuria+groupsinterventioncount121130.844a120120.307a(%)92.3%7.7%100.0%100.0%.0%100.0%placebocount1611711112(%)94.1%5.9%100.0%91.7%8.3%100.0%totalcount2823023124(%)93.3%6.7%100.0%95.8%4.2%100.0%apearson chi-square.bfisher’s exact test. |
| PubMedID- 20823346 | We have previously highlighted the importance of conventional cardiovascular risk factors in the etiology of clinical neuropathy in individuals with type 1 diabetes (9), but their association to earlier abnormalities in nerve conduction is less certain. |
| PubMedID- 25591852 | Conclusions: autonomic dysfunction is present in early stages of retinopathy, nephropathy, and peripheral neuropathy in patients with type 1 diabetes. |
| PubMedID- 24211151 | Introduction: painful peripheral neuropathy in people with type 1 diabetes is a disabling and costly complication. |
| PubMedID- 23340890 | Over the last 30 years, a marked improvement in diabetic nephropathy, retinopathy, and neuropathy was observed in patients with type 1 diabetes mellitus (t1dm) (1–3). |
| PubMedID- 24629408 | Methods: the landmark study is a 4-year, two-site, natural history study of three participant groups: type 1 diabetes with neuropathy (t1w), type 1 diabetes without neuropathy (t1wo) and control participants without diabetes or neuropathy. |
| PubMedID- 25538321 | Corneal confocal microscopy shows an improvement in small-fiber neuropathy in subjects with type 1 diabetes on continuous subcutaneous insulin infusion compared with multiple daily injection. |
| PubMedID- 22503144 | Peripheral neuropathy in children with type 1 diabetes. |
| PubMedID- 23929529 | Several clinical trials have demonstrated that treating hyperglycemia, a component of the metabolic syndrome, has a significant effect on reducing the incidence of neuropathy in those with type 1 diabetes. |
| PubMedID- 22608666 | While glucose control substantially decreases the development of neuropathy in those with type 1 diabetes, the effect is probably much smaller in those with type 2 diabetes. |
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