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PedAM

Pediatric Disease Annotations & Medicines




Disease neuropathy
Phenotype C0004153|atherosclerosis
Sentences 3
PubMedID- 23922510 In addition to microvascular changes, such as nephropathy, retinopathy and neuropathy, diabetes leads to atherosclerosis or macrovascular changes.
PubMedID- 21611069 Premature and advanced atherosclerosis, together with peripheral neuropathy, impaired cellular immunity and impaired wound healing make cli a complex problem among diabetic patients.
PubMedID- 23921246 Cox proportional hazards regression analysis revealed end-stage renal disease (hazard ratio [hr], 3.9; 95% confidence interval [ci], 2.3-6.5), chronic renal insufficiency (hr, 2.2; 95% ci, 1.5-3.3), atherosclerosis without diabetic neuropathy (hr, 2.9; 95% ci, 1.5-5.7), atherosclerosis with diabetic neuropathy (hr, 9.1; 95% ci, 3.7-22.5), and initial major amputation (hr, 1.8; 95% ci, 1.3-2.6) were independently predictive of subsequent contralateral major amputation.

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