PedAM
Pediatric Disease Annotations & Medicines
| Disease | neural tube defects |
| Phenotype | C0016412|folate deficiency |
| Sentences | 6 |
| PubMedID- 22443202 | To reduce the incidence of neural tube defect pregnancies associated with folate deficiency, the us food and drug administration (fda) adopted requirements for folate fortification of many food products starting in 1996 [31]. |
| PubMedID- 23127121 | folate deficiency increases the risk of chronic diseases, including neural tube defects (ntds) in infants, megaloblastic anemia, cardiovascular disease, and some cancers in adults. |
| PubMedID- 22975411 | Objective: maternal folate deficiency is associated with neural tube defects (ntds), the most common congenital birth defect at maternity hospital, kathmandu, nepal. |
| PubMedID- 22303378 | For instance, it is well-known that folate deficiency is associated with neural tube defects (ntd; daly et al., 1995), animal studies have indicated the necessity of sufficient methyl group availability for proper neural tube development (dunlevy et al., 2006), and hypomethylation of long interspersed nucleotide elements (line) and genomic dna has been associated with increased risk of ntds in humans (wang et al., 2010). |
| PubMedID- 23936521 | Independently, vit-b12 has a significant role in early neuronal and brain development [8] and folate deficiency is associated with neural tube defects (ntd) while errors of homocysteine metabolism promote a range of clinical complications [9]. |
| PubMedID- 24694212 | Subtler effects include maternal micronutrient deficiencies, such as iron deficiency anemia [164], and conditions that directly affect the fetus, such as neural tube defects associated with folate deficiency [165]. |
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