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PedAM

Pediatric Disease Annotations & Medicines




Disease nephritis
Phenotype C0033687|proteinuria
Sentences 25
PubMedID- 26266393 The most common renal manifestation of igg4-related disease is tubulointerstitial nephritis marked with proteinuria, hematuria, decreased kidney function, hypocomplementemia, and radiologic abnormalities.
PubMedID- 21651460 In addition to the toxic effects of proteinuria, patients with lupus nephritis may exhibit other factors that contribute to tubular dysfunction, such as pathogenic antitubular basement membrane antibodies.
PubMedID- 25670710 Objectives: the aim of this study was to evaluate the correlation and agreement of spot urine protein/creatinine (p/c) ratio with 24 h proteinuria in patients with lupus nephritis (ln) under different scores of activity index (ai).
PubMedID- 24429170 We aimed (1) to determine the recovery time from proteinuria in patients with lupus nephritis (ln) receiving standard treatment, and (2) to determine whether the initial level of proteinuria predicts time to improvement.
PubMedID- 25880729 Besides producing a reversible renal failure, nsaids are known to cause acute interstitial nephritis (ain) with hematuria, proteinuria and flank pain [14] as well as acute tubular necrosis (atn).
PubMedID- 25605554 Methods: patients from the euro-lupus nephritis trial with proteinuria, serum cr, and urinary rbc measurements at 3, 6, or 12 months and with a minimum of 7 years of followup were included (n = 76).
PubMedID- 26537989 An 8-year-old girl with hematuria and proteinuria due to anti-gbm nephritis was diagnosed with hematuria and proteinuria during a school urine screening program.
PubMedID- 23193442 A long-standing paradigm, which holds that nucleosomes represent the primary (auto)antigen-inducing anti-dna antibodies, is questioned by the observations that foreign dna-protein complexes can also serve as efficient antigens for induction of anti-dna antibodies that cause lupus-like nephritis with proteinuria and glomerular igg deposits [8, 9].
PubMedID- 24741600 Sle patients with severe disease conditions such as higher sledai, elevated 24 h proteinuria excretion, or presence of autoantibodies or lupus nephritis also showed significantly higher plasma smer levels compared to those without.
PubMedID- 25984093 Interestingly, the amount of foot process effacement is the only factor that has been identified to be involved with nephrotic proteinuria in patients with lupus nephritis class ii or lupus-associated mcd.
PubMedID- 24500387 Aggressive treatment is necessary for continuous high-range proteinuria in cases of pediatric henoch-schonlein purpura nephritis (hspn) as the long-term prognosis is sometimes poor.
PubMedID- 20937089 When damage occurs, the interaction between immune-related factors and damaged cells can lead to foot process retraction, proteinuria, destruction of the filtration barrier, nephritis, and subsequently induction of end-stage renal failure and death (esrf/death) [4,5].
PubMedID- 23257405 Aliskiren attenuates proteinuria in mice with lupus nephritis by a blood pressure-independent mechanism.
PubMedID- 22382248 Interstitial nephritis with proteinuria >1 g/day is uncommon and almost always the result of drug-induced atin with an associated minimal change glomerulonephritis (gn).
PubMedID- 21441821 The s-upci and the 24-hup can be used interchangeably for follow-up in lupus nephritis patients with proteinuria of less than 2 g/d.
PubMedID- 25649369 Lupus nephritis usually presents with abnormal urinalysis, proteinuria, and/or renal insufficiency.
PubMedID- PMC3194612 She has, severe progressive nephritis with nephrotic syndrome (proteinuria 4 g/24 h), hematuria, hypoalbuminemia, high positive autoimmunity tests (ana, anti dna), iv class of lupus-nephritis by kidney biopsy.
PubMedID- 22470387 Consequently, we hypothesized that dha administration might suppress proteinuria in rats with nts nephritis by preventing a reaction in the heterologous phase.
PubMedID- 23281659 Clinical features of this x-linked syndrome are defects in the gbm resulting in hematuria, progressive nephritis with proteinuria and declining renal function [57,58].
PubMedID- 23302718 Cyclosporine treatment significantly reduced proteinuria in rats with passive heymann nephritis, concomitant with downregulation of c-mip in podocytes.
PubMedID- 25684013 For example, drug exposure can result in the release of permselectivity promoting factors from activated inflammatory or immune cells, causing mcd.13 another possible mechanism of mcd is via direct toxin effects on glomerular epithelial cells, resulting in abnormal permeability and effacement of the foot processes.13 neugarten, et al.7 reported the first case of rifampicin-induced nephrotic syndrome, and described the patient as having acute interstitial nephritis with heavy proteinuria and effacement of the glomerular epithelial cells.
PubMedID- 24803916 In conclusion, it seems that immunoadsorption can help to reduce proteinuria safely in patients with membranous lupus nephritis and persistent nephrotic range proteinuria despite several months of acei/arb, mycophenolic acid and hydroxychloroquine treatment.
PubMedID- 26496290 Similarly, pitashny et al34 disclosed a positive correlation between urinary ngal excretion and activity of nephritis associated with proteinuria in adult patients with systemic lupus erythematosus.
PubMedID- 24650571 In conclusion, the measurement of daily or weekly urinary thg and β2m excretion is a more practical method for monitoring the progression of lupus nephritis as compared with proteinuria or serial kidney biopsy alone as seen in figures 6 and7.
PubMedID- 26351598 A 27-year-old latina woman received a living related transplant from her mother for end stage renal disease (esrd) secondary to advanced lupus nephritis and presented with nephrotic range proteinuria 6 months after transplantation.

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