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PedAM

Pediatric Disease Annotations & Medicines




Disease n syndrome
Phenotype C0949664|tauopathies
Sentences 1
PubMedID- 24069033 As described in previous section, the kinase dyrk1a exerts an important regulation on the as of the tau gene, thus strongly suggesting that its increased dosage due to the trisomy of chromosome 21 could be the main cause of the early onset of tauopathies in patients with down syndrome [103].

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