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PedAM

Pediatric Disease Annotations & Medicines




Disease n syndrome
Phenotype C0026946|fungal infection
Sentences 2
PubMedID- 22707953 Clinically, severe fungal infections occur in patients with immune reconstitution syndrome (irs), an entity characterized by local and systemic reactions that have both beneficial and deleterious effects on infection (singh and perfect, 2007).
PubMedID- 22973279 The conceptual principle highlighting a truly bipolar nature of the inflammatory process in infection is best exemplified by the occurrence of severe fungal infections in patients with immune reconstitution syndrome, an entity characterized by localized and systemic inflammatory reactions, worsening disease in opportunistic and non-opportunistic infections, that are associated with immunological recovery (gupta and singh, 2011; perfect, 2012).

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