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PedAM

Pediatric Disease Annotations & Medicines




Disease myoclonus
Phenotype C0027819|neuroblastoma
Sentences 6
PubMedID- 25224062 Objective: to investigate the efficacy of combined modality therapy for neuroblastoma in children associated with opsoclonus-myoclonus syndrome (oms-nb).
PubMedID- 20110181 Objective: to compare the clinical data at diagnosis, treatment and neurological outcome in 34 children with opsoclonus-myoclonus syndrome (oms) associated with a detected neuroblastoma or not.
PubMedID- 26445726 Anti-hu antibodies are extremely rare in children, but they have been observed in neuroblastoma with or without opsoclonus-myoclonus syndrome or in limbic encephalitis without associated malignancy.1 however, anti-hu antibodies are not typically associated with clinical features of rasmussen encephalitis (re).
PubMedID- 22247816 Children with opsoclonus myoclonus resulting from a neuroblastoma often retain neurological sequelae.
PubMedID- 23198199 Clinical responses to rituximab in a case of neuroblastoma with refractory opsoclonus myoclonus ataxia syndrome.
PubMedID- 21941489 Furthermore, in young children, neuroblastoma exceptionally manifests with paraneoplastic opsoclonus-myoclonus-ataxia (poma) due to antineuronal nuclear (anti-hu) antibodies [3] which have also been associated with gastrointestinal disturbances, such as constipation, gut dismotility and paralytic ileus [4].

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