PedAM
Pediatric Disease Annotations & Medicines
| Disease | myocardial infarction |
| Phenotype | C0002871|anaemia |
| Sentences | 4 |
| PubMedID- 21267962 | The significance of anaemia in patients with acute st-elevation myocardial infarction undergoing primary percutaneous coronary intervention. |
| PubMedID- 24051679 | Prognostic impact of anaemia on patients with st-elevation myocardial infarction treated by primary pci. |
| PubMedID- 23787722 | On the other hand, anaemic patients showed a less frequent history of ischaemic chf (p = 0.035) and previous myocardial infarction compared with patients without anaemia (p = 0.001).table 1baseline demographics, clinical characteristics, and main laboratory measurements of the study population according to the presence or absence of anaemia at baseline and treatment arm (ferric carboxymaltose or placebo)anaemic (n = 232)non-anaemic (n = 227)fcm (n = 155)placebo (n = 77)fcm (n = 149)placebo (n = 78)age, years68.2 (10.7)67.9 (11.2)67.5 (9.9)67.0 (11.2)female, n (%)92 (59.4%)45 (58.4%)67 (45.0%)40 (51.3%)caucasian, n (%)154 (99.4%)77 (100.0%)149 (100.0%)78 (100.0%)nyha class ii, n (%)22 (14.2%)13 (16.9%)31 (20.8%)16 (20.5%)nyha class iii, n (%)133 (85.8%)64 (83.1%)118 (79.2%)62 (79.5%)ejection fraction, %31.8 (5.8)32.6 (6.5)32.1 (5.2)33.4 (5.6)body weight, kg75.9 (15.5)77.5 (16.2)78.0 (12.7)77.7 (16.5)body mass index, kg/m228.1 (5.3)28.2 (5.2)27.9 (4.1)28.0 (5.0)systolic blood pressure, mmhg126 (15)127 (14)126 (15)126 (15)diastolic blood pressure, mmhg77 (10)77 (10)77 (9)75 (10)pulse rate, b.p.m.71 (12)71 (13)70 (11)73 (11)6 min walk test distance, m251 (96)251 (117)297 (108)287 (98)ischaemic, n (%)119 (76.8%)58 (75.3%)126 (84.6%)65 (83.3%)cardiovascular risk factor hypertension, treated with drugs, n (%)123 (79.4%)59 (76.6%)120 (80.5%)69 (88.5%) dyslipidaemia, treated with drugs, n (%)66 (42.6%)38 (49.4%)78 (52.3%)32 (41.0%) diabetes mellitus, n (%)51 (32.9%)16 (20.8%)42 (28.2%)21 (26.9%) history of af, n (%)52 (33.5%)25 (32.5%)42 (28.2%)19 (24.4%)medical history previous myocardial infarction, n (%)74 (47.7%)39 (50.6%)94 (63.1%)51 (65.4%) known angina pectoris, n (%)84 (54.2%)38 (49.4%)87 (58.4%)51 (65.4%) previous stroke, n (%)12 (7.7%)5 (6.5%)12 (8.1%)4 (5.1%) previous cabg, n (%)17 (11.0%)7 (9.1%)17 (11.4%)6 (7.7%) previous ptca, n (%)19 (12.3%)11 (14.3%)26 (17.4%)9 (11.5%)laboratory measurements haemoglobin, g/l109 (8)108 (8)129 (7)130 (9) red blood cell count, 1012/l4.0 (0.5)4.0 (0.4)4.3 (0.4)4.4 (0.4) mean corpuscular volume, fl89.4 (7.9)90.6 (7.3)93.9 (7.6)92.7 (6.0) iron, μmol/l12.7 (16.1)9.3 (4.4)13.4 (5.6)13.9 (6.0) serum ferritin, μg/l51.3 (62.9)59.2 (68.4)53.7 (44.4)60.9 (65.0) transferrin, g/l3.01 (0.54)2.95 (0.58)2.91 (0.48)2.83 (0.43) transferrin saturation, %16.6 (15.6)13.5 (7.4)18.8 (8.4)19.8 (8.1) folate (folic acid), nmol/l18.2 (10.4)16.6 (8.5)16.6 (8.0)15.5 (8.0) vitamin b12, pmol/l289 (132)299 (126)282 (128)293 (129) creatinine, μmol/l110 (60)114 (69)101 (35)99 (35) blood urea nitrogen, mg/dl25.4 (13.1)27.1 (16.0)22.5 (10.9)23.1 (11.3) estimated glomerular filtration rate, ml/min61.9 (22.6)61.7 (26.5)65.8 (19.6)67.9 (23.9) potassium, mmol/l4.63 (0.64)4.57 (0.52)4.66 (0.59)4.58 (0.53) sodium, mmol/l141 (3)140 (3)141 (3)141 (3) total bilirubin, μmol/l9.9 (7.4)9.9 (5.9)11.0 (5.6)11.1 (6.3) alanine aminotransferase, u/l20.4 (11.7)17.9 (7.5)20.7 (12.9)19.7 (8.7) aspartate aminotransferase, u/l23.2 (10.4)22.4 (7.0)22.9 (10.5)22.4 (7.4) uric acid, mmol/l0.38 (0.13)0.40 (0.14)0.37 (0.12)0.40 (0.11) c-reactive protein, mg/l7.62 (4.55)9.71 (4.56)7.30 (6.07)8.47 (6.35)concomitant treatment diuretics, n (%)141 (91.0%)69 (89.6%)139 (93.3%)71 (91.0%) agents blocking renin–angiotensin system, n (%)140 (90.3%)69 (89.6%)141 (94.6%)72 (92.3%) beta-blockers, n (%)132 (85.2%)64 (83.1%)130 (87.2%)65 (83.3%) cardiac glycosides, n (%)24 (15.5%)14 (18.2%)22 (14.8%)11 (14.1%) antiarrythmics, class i and iii, n (%)20 (12.9%)5 (6.5%)17 (11.4%)6 (7.7%)antiplatelet agents, n (%)100 (64.5%)47 (61.0%)89 (59.7%)50 (64.1%) anticoagulant agents, n (%)35 (22.6%)11 (14.3%)32 (21.5%)11 (14.1%) insulin and analogues, n (%)18 (11.6%)4 (5.2%)9 (6.0%)5 (6.4%) oral hypoglycaemic agents, n (%)27 (17.4%)9 (11.7%)22 (14.8%)13 (16.7%) lipid-lowering agents, n (%)61 (39.4%)35 (45.5%)81 (54.4%)37 (47.4%)continuous variables are expressed as mean (standard deviation) and categorical variables as number of cases (percentage).cabg, coronary artery bypass grafting; fcm, ferric carboxymaltose; ptca, percutaneous transluminal coronary angioplasty. |
| PubMedID- 22691691 | Brain tissue samples from normal (n = 7; 2 females and 5 males) and alzheimer’s patients (n = 11; 6 females and 5 males) were used, with agonal states including: bronchopneumonia, cardiac failure, hypertension, pulmonary embolus, sideroblastic anaemia, coronary occlusion, carcinoma of left kidney, myocardial infarction and ischemic heart disease. |
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