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PedAM

Pediatric Disease Annotations & Medicines




Disease myelomeningocele
Phenotype C0005697|neurogenic bladder
Sentences 7
PubMedID- 26106487 However, in our study, myelomeningocele with a neurogenic bladder was the most common underlying predisposing factor while vur with the source was present in only 10 (13%) patients.
PubMedID- 24235794 [12] the indications for this procedure include refractory neurogenic bladder (with or without myelomeningocele), refractory idiopathic bladder dysfunction, severe urethral stricture disease as an adjunct to reconstruction in congenital urogenital abnormalities (cloacal exstrophy, posterior urethral valves, epispadias, and prune belly syndrome).
PubMedID- 22720170 More knowledge about botulinum toxin therapeutic effects in cases of neurogenic bladder due to myelomeningocele (93%).
PubMedID- 24453796 In these preliminary studies, seven patients with neurogenic bladder due to myelomeningocele were identified as candidates for cystoplasty.
PubMedID- 26090342 Although the idea was conceived in the 1950s, and a plethora of natural and synthetic biomaterial scaffolds has been used in experimental animals, their clinical application remains a formidable challenge.139 in a meta-analysis of 28 preclinical and two clinical studies, the reviewers found a poor correlation between the initial experimental successes in healthy animals and those reported in clinical trials.140 in the first clinical study, seven patients with neurogenic bladder due to myelomeningocele underwent bladder augmentation using autologous bioengineered constructs.141 after nearly 4 years of follow-up, bladder pressure had decreased while capacity and compliance had increased.
PubMedID- 24718880 The exclusion criteria involved coexisting abnormalities of the urogenital tract, in particular ureterocele, ectopic ureters, posterior urethral valves, neurogenic bladder due to myelomeningocele and urge incontinence.
PubMedID- 23301927 Because of associated neurogenic bladder dysfunction, children with myelomeningocele have an increased risk of urinary tract infections and, ultimately, of kidney damage.

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