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PedAM

Pediatric Disease Annotations & Medicines




Disease myeloid leukemia
Phenotype C1261473|sarcomas
Sentences 5
PubMedID- 24552499 Disseminated myeloid sarcomas-a rare presentation of acute myeloid leukemia.
PubMedID- 24791856 We report a humanized experimental leukemia model where xenografts develop aggressive acute myeloid leukemia (aml) with disseminated myeloid sarcomas within 4 weeks following transplantation of cord blood transduced with vectors expressing bcr-abl1 and a dominant-negative isoform of ikaros, ik6.
PubMedID- 23580888 They are also known as chloromas, myeloblastomas, myelocytomas, chloroleukemia and granulocytic sarcomas and are associated with acute myeloid leukemia (aml) and blastic transformation of chronic myeloproliferative disorders (chronic myeloid leukemia, polycythemia vera and primary myelofibrosis) and myelodysplastic syndromes.
PubMedID- 26295265 The increased sensitivity to hypomorphic atr reduction was observed in sarcomas expressing active forms of h-rasg12v, acute myeloid leukemia driven by mll-enl, and in c-myc-driven lymphoma [71,72,73].
PubMedID- 24385760 In conclusion, myeloid leukemias might present with granulocytic sarcomas, particularly in skin without bone marrow involvement.

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