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PedAM

Pediatric Disease Annotations & Medicines




Disease myeloid leukemia
Phenotype C0026985|myelodysplasia
Sentences 30
PubMedID- 21102413 Following the current world health organization classification algorithm, these cases were classified as: 13 acute myeloid leukemia with myelodysplasia-related changes, 3 therapy-related acute myeloid leukemia, and 1 chronic myelogenous leukemia blast crisis, and one unclassifiable due to insufficient clinical information.
PubMedID- 22950073 Detection of runx1-mecom fusion gene and t(3;21) in a very elderly patient having acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 20954271 Acute myeloid leukemia with myelodysplasia-related changes with erythroid differentiation involving pleural fluid: a case report and brief cytopathologic review.
PubMedID- 22911588 To the best of our knowledge, this is the first report of acute myeloid leukemia with myelodysplasia-related changes with i(17q) after the use of a hypomethylating agent.
PubMedID- 25379617 Faggot-like cells observed in acute myeloid leukemia with myelodysplasia-related changes mimicking acute promyelocytic leukemia.
PubMedID- 25860933 Acute myeloid leukemias (aml) with myelodysplasia-related changes (aml-mrc) are defined by the presence of multilineage dysplasia (mld), and/or myelodysplastic syndrome (mds)-related cytogenetics, and/or previous mds.
PubMedID- 25669040 Four cases were presented and discussed mainly from the viewpoint of cellular morphology: two cases of acute myeloid leukemia (aml) with myelodysplasia-related changes, one case of adult t-cell leukemia/lymphoma, and one case of chronic myelogenous leukemia in the blast phase.
PubMedID- 22154053 The latter include acute erythroid leukemia (erythroid-myeloid and pure erythroid leukemia subtypes) as well as some cases of myelodysplastic syndromes, acute myeloid leukemia with myelodysplasia-related changes, and therapy-related myeloid neoplasms.
PubMedID- 20980053 Novel variant form of t(11;22)(q23;q13)/mll-ep300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 20473273 We collected 90 cases and separated them into four diagnostic groups: acute erythroid leukemia, erythroleukemia or erythroid/myeloid type (n=20); acute myeloid leukemia with myelodysplasia-related changes (n=22); therapy-related acute myeloid leukemia (n=32); and refractory anemia with excess blasts and preceding or concurrent history of erythropoietin therapy for anemia (n=16).
PubMedID- 26084204 Allogeneic hematopoietic stem cell transplantation (allo-hsct) overcomes poor prognosis of acute myeloid leukemia with myelodysplasia-related changes (aml-mrc).
PubMedID- 20603581 [clinical importance of morphological multilineage dysplasia in acute myeloid leukemia with myelodysplasia related changes].
PubMedID- 21091147 The erythroid/myeloid subtype of acute erythroleukemia is closely related to acute myeloid leukemia with myelodysplasia-related changes, and is frequently characterized by morphological dysplasia and complex karyotype.
PubMedID- 24661537 Temporomandibular joint arthritis as an initial presentation of acute myeloid leukemia with myelodysplasia-related changes: a report of an unusual case.
PubMedID- 26239249 Mds: myelodysplastic syndrome, aml-mrc: acute myeloid leukemia with myelodysplasia related changes, ptd: partial tandem duplication, cn-aml: cytogenetically normal acute myeloid leukemia.
PubMedID- 21768886 We report a unique pediatric case of hypergranular acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 26071461 Most cases of amkl in adults would be classified as acute myeloid leukemia with myelodysplasia-related changes according to the who classification, but this approach deemphasizes their unique clinical, morphologic, and immunophenotypic features.
PubMedID- 22186000 Acute myeloid leukemia with myelodysplasia-related changes mimicking acute promyelocytic leukemia.
PubMedID- 22022200 For example, we were able to identify a very rare npm1-mlf1 rearrangement from an acute myeloid leukemia with myelodysplasia-related changes (aml-mrc) patient who accompanied a complex karyotype by utilizing the multiplex rt-pcr testing method (2).
PubMedID- 26071460 Acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 24716233 Giant multilobated mastocytes(promastocytes) in the setting of a refractory acute myeloid leukemia with myelodysplasia-related changes and monosomal karyotype.
PubMedID- 24941894 Acute myeloid leukemia with myelodysplasia-related changes showing basophilic differentiation.
PubMedID- 24824767 Acute myeloid leukemia (aml) with myelodysplasia-related changes is characterized by the presence of multilineage dysplasia (mld), frequently related to high-risk cytogenetics and poor outcome.
PubMedID- 24695467 Granulocyte, monocyte and blast immunophenotype abnormalities in acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 21447369 Impaired mitochondrial gene transcription in myelodysplastic syndromes and acute myeloid leukemia with myelodysplasia-related changes.
PubMedID- 23874874 Single missense mutations within the runt domain severely diminish or even ablate binding runx1 dna binding and are associated with myelodysplasia and the development of acute myeloid leukemia, perhaps by haploinsufficiency and lowered gene dosage or by interference with the homodimerization of wildtype runx1 or its binding to cbfβ.
PubMedID- 24861848 Characteristics of acute myeloid leukemia with myelodysplasia-related changes: a retrospective analysis in a cohort of chinese patients.
PubMedID- 25975285 On multivariable analysis, neither acute myeloid leukemia with myelodysplasia-related changes nor acute myeloid leukemia-not evaluable showed significantly different event-free survival compared with acute myeloid leukemia-not otherwise specified in the 137 patients treated with induction chemotherapy.
PubMedID- 22535592 Acute myeloid leukemia with myelodysplasia-related changes are characterized by a specific molecular pattern with high frequency of asxl1 mutations.
PubMedID- 24852219 Peripheral blood features of acute myeloid leukemia with myelodysplasia-related changes developing in a patient with sickle cell anemia.

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