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PedAM

Pediatric Disease Annotations & Medicines




Disease myeloid leukemia
Phenotype C0001815|myelofibrosis
Sentences 2
PubMedID- 24315414 We report the molecular cloning and functional characterization of a novel fgfr1op (exon 11)-ret (exon 11) gene fusion event (named fgfr1op-ret), mediated by a reciprocal translocation t(6; 10)(q27; q11), in a patient affected by primary myelofibrosis (pmf) with secondary acute myeloid leukemia (aml).
PubMedID- 24201159 Transformed acute myeloid leukemia in myelofibrosis results in a median survival of less than 5 months.

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