PedAM
Pediatric Disease Annotations & Medicines
| Disease | myelodysplastic syndrome |
| Phenotype | C0030312|bone marrow failure |
| Sentences | 4 |
| PubMedID- 25741600 | Tumorigenesis initiated by repeated cell attrition and repopulation, as confirmed in different genetic models, has parallels in human cancers, exemplified in therapy-induced secondary malignancies and myelodysplastic syndromes in patients with congenital bone marrow failure syndromes. |
| PubMedID- 24800039 | It has been shown to be effective in patients with bone marrow failure due to myelodysplastic syndromes (mds), graft failure, chemotherapy, or aplastic anemia. |
| PubMedID- 25332625 | Fanconi's anemia is primarily an autosomal recessive genetic disorder characterized by congenital abnormalities, defective haematopoiesis leading to bone marrow failure and increased risk of development of myelodysplastic syndrome, acute myeloid leukemia and solid tumours. |
| PubMedID- 24032679 | The pathogenesis of bone marrow failure in myelodysplastic syndromes (mds) is an unresolved mystery. |
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