PedAM
Pediatric Disease Annotations & Medicines
| Disease | muscular dystrophy |
| Phenotype | C0878544|cardiomyopathies |
| Sentences | 1 |
| PubMedID- 23324314 | A hypothesis to explain the underlying pathophysiology of cardiomyopathies associated with muscular dystrophy is that recurrent membrane injury leads to an increased influx of calcium [4] which then causes downstream effects such as activation of calcium-dependent hypertrophic pathways [5], reactive oxygen species [6] and cell death through necrosis with mitochondrial defects [7]. |
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