PedAM
Pediatric Disease Annotations & Medicines
| Disease | multiple myeloma |
| Phenotype | C1704214|xanthogranuloma |
| Sentences | 3 |
| PubMedID- 25541670 | Generalized necrobiotic xanthogranuloma in a patient with multiple myelomaus patient with isolated neutropenia and diminished expression of cd55 and cd59 similar to paroxysmal nocturnal hemoglobinuria. |
| PubMedID- 23271884 | Hematologic malignancy in patients with necrobiotic xanthogranuloma in the form of multiple myeloma, leukemia, and lymphoma has been reported.1,2 the pathogenesis of necrobiotic xanthogranuloma is not well understood, but borrelia spirochetal infection has been proposed because organisms have been identified within the lesions.3 others have hypothesized that there is enhanced monocyte phagocytic activity leading to lipid accumulation and a subsequent giant cell inflammatory response in the skin.4 the relationship between the hematologic abnormalities and skin lesions is not currently understood. |
| PubMedID- 25809408 | Necrobiotic xanthogranuloma with multiple myeloma. |
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