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PedAM

Pediatric Disease Annotations & Medicines




Disease mental depression
Phenotype C0853193|bipolar i disorder
Sentences 9
PubMedID- 22296512 Conclusions: symptomatic improvements assessed here suggest that aripiprazole monotherapy at the doses studied may provide some improvements in core symptoms of depression in patients with bipolar i disorder who were more severely depressed.
PubMedID- 23391680 Methods: two focus groups were conducted using nominal group technique via a web interface and teleconference to elicit barriers that psychiatrists face in managing depression in patients with bipolar i disorder.
PubMedID- PMC2991978 A major trend in recent years has been the recognition that antipsychotic drugs are useful not only in mania and hypomania, but in preventing both mania and depression in patients with bipolar i disorder.
PubMedID- 22420593 The specific neurophysiology responsible for depression in bipolar i disorder is unknown but previous neuroimaging studies suggest impairments in corticolimbic regions that are responsible for regulating emotion.
PubMedID- 21672493 Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar i disorder: a randomized, double-blind, placebo-controlled trial.
PubMedID- 22519923 Patients in this trial had bipolar i disorder with mania, depression or a mixed episode as the index episode, and the trial included only patients who were responsive to acute phase quetiapine, which may have introduced a positive bias in favour of quetiapine over lithium during maintenance therapy.
PubMedID- 26330288 Specifically, patients were aged 18 to 65 years and had bipolar i disorder with current non-psychotic depression according to the diagnostic and statistical manual of mental disorders (fourth edition, text revision; dsm-iv-tr) criteria (american psychiatric association, 2000), as determined by the structured clinical interview for dsm-iv, clinical trials (scid-ct) (first et al., 2007).
PubMedID- 22329476 Conclusion: to our knowledge, this is the first report of coupling a molecular marker of vulnerability (allergen-specific ige) with a specific environmental trigger (airborne allergens) leading to exacerbation of depression in patients with bipolar i disorder.
PubMedID- 23507138 A systematic review of the evidence for the treatment of acute depression in bipolar i disorder.

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