| Disease | mental depression |
| Phenotype | C0149931|migraine |
| Sentences | 31 |
| PubMedID- 25754599 | Among adolescents without recurrent headache at baseline, higher scores for symptoms of anxiety and depression were associated with new onset migraine 4 years later [13•]. |
| PubMedID- 24762133 | Anxiety and depression associated with migraine may contribute to increased food intake in migraineurs by affecting appetite regulators. |
| PubMedID- 22466285 | Possible risk factors for depression in migraineurs included headache intensity of first onset of migraine, migraine with presymptom, migraine with family history and migraine disability. |
| PubMedID- 23799958 | Population based studies demonstrate that depression is comorbid with migraine [11,12]. |
| PubMedID- 21635773 | In this study, we investigate the association between mthfr c677t polymorphism and migraine in a sample of cases of depression and healthy controls. |
| PubMedID- 25595046 | Among adolescents without recurrent headache at baseline, symptoms of anxiety and depression were associated with new onset migraine four years later and attention difficulties at baseline were associated with new onset non-classifiable headache. |
| PubMedID- 25754865 | An initial excess of neuronal activity in migraine leads to cortical spreading depression and aura, with the subsequent recruitment of the trigeminal nucleus leading to central sensitization and pain. |
| PubMedID- 21188255 | In these, the risk of new onset migraine in people with depression ranged from 2.8 to 3.5. |
| PubMedID- 24224086 | For women, the age- and race-adjusted odds of depression among those with migraine were 2.17 times higher than those without migraine (95% ci = 1.97, 2.40) and were reduced to 1.89 (95% ci = 1.71, 2.10) in the fully adjusted model. |
| PubMedID- 20071666 | Odds ratios for depression in patients with migraine were 1.29 (95% confidence interval [ci] 0.98-1.70) for mo and 1.70 (95% ci 1.28-2.24) for ma. |
| PubMedID- 25494868 | Headache frequency per month was remarkably higher in subjects having migraine with anxiety and depression (median [25-75 percentile values], 8.0 [2.5-21.0]) than in those having migraine with anxiety alone (2.0 [1.0-5.0], p = 0.003), migraine with depression alone (1.0 [0.3-4.0], p = 0.001), and migraine without anxiety or depression (1.0 [0.3-3.0], p < 0.001). |
| PubMedID- 24147100 | However, a more comprehensive experimental design is needed to reveal the accurate roles of these reho abnormalities in the pathology of migraine with depression symptoms. |
| PubMedID- 22991044 | Aura migraine is associated with cortical spreading depression (csd), which is a short-lasting intense wave of neuronal and glial cell depolarization that slowly progresses over the cortex and is followed by long-lasting neuronal activity depression. |
| PubMedID- 21210177 | The overall risk estimate gave an odd of depression for people with migraine with respect to people without migraine of 2.2, with a 95% confidence interval of 2.0–2.3. |
| PubMedID- 23395476 | Anxiety and depression are associated with migraine and pain in general: an investigation of the interrelationships. |
| PubMedID- 20108021 | However, based on the prevalence of major depression in patients with migraine without aura (23.1%) and in those with tension-type headache (25.5%), a significantly greater number of patients would be needed in order for this difference to achieve statistical significance. |
| PubMedID- 24182892 | migraine was more associated with depression than the other types of headache. |
| PubMedID- 26174509 | Comorbid depression in patients with migraine may have important clinical implications. |
| PubMedID- 23080079 | Also, functional impairment related to the presence of self-reported depression in patients with chronic migraine should be considered in terms of long-term cognitive changes. |
| PubMedID- 23055110 | The main finding of this study was that chronic migraine is strongly associated with depression symptoms, regardless of demographic data. |
| PubMedID- 21499917 | The comorbidity of migraine with depression has led to suggest a shared pathogenesis [22]. |
| PubMedID- 24770422 | Allodynia is associated with a higher prevalence of depression in migraine patients. |
| PubMedID- 24340013 | Strong evidence from clinical correlations with functional brain imaging studies suggests that the migraine aura is due to cortical spreading depression (csd) originating in the occipital cortex [6]. |
| PubMedID- 21394551 | [43] reported, in a population study from turkey, that major depression was strongly associated with migraine, and although the prevalence of major depression was higher in women (22% vs. 9%), in persons with migraine this gender difference in prevalence was no longer present (33% prevalence of major depression in women vs. 32% in men). |
| PubMedID- 20625916 | migraine is comorbid with depression in the general population [14–16] and our study extends this association to ms population. |
| PubMedID- 21444643 | For example, cortical spreading depression (csd), associated with migraine development, is increased in frequency with prolonged use of topiramate or paracetamol. |
| PubMedID- 22644195 | Based on these findings, in mo patients the high frequency of migraine attacks, comorbidity with depression, and the tendency to develop arterial hypertension should require particular attention and careful management to prevent evolution into cm. |
| PubMedID- 25644990 | Discussion and conclusion: clinical implications and treatment strategies for migraine patients with comorbid depression are discussed. |
| PubMedID- 24118449 | Recent progress in migraine pathophysiology: role of cortical spreading depression and magnetic resonance imaging. |
| PubMedID- 24220568 | The neuronal mechanisms of migraine may be attributed to cortical spreading depression (csd); consequently, csd has been widely studied for understanding the pathophysiology of migraine. |
| PubMedID- 20647240 | We attempted to compare the mechanisms by which cardiac myxoma and other cardiac abnormalities could trigger cortical spreading depression leading to migraine with aura. |
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