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PedAM

Pediatric Disease Annotations & Medicines




Disease mental depression
Phenotype C0036337|schizoaffective disorder
Sentences 3
PubMedID- 22134460 Case report on the management of depression in schizoaffective disorder, bipolar type focusing on lithium levels and measurement-based care.
PubMedID- 23512949 Molecular genetic studies point to potential risk loci of psychotic depression shared with schizoaffective disorder (1q42, 22q11, 19p13), depression, bipolar disorder, and schizophrenia (6p, 8p22, 10p13-12, 10p14, 13q13-14, 13q32, 18p, 22q11-13) and several vulnerability genes possibly contributing to an increased risk of psychotic symptoms in depression (eg, bdnf, dbh, dtnbp1, drd2, drd4, gsk-3beta, mao-a).
PubMedID- 22018413 Three studies [35,37,65], however, found that better cognitive insight (composite index and sr) is related to worse depression in patients with schizophrenia or schizoaffective disorder when looking at a cross-section.

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