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PedAM

Pediatric Disease Annotations & Medicines




Disease mental depression
Phenotype C0022336|creutzfeldt-jakob disease
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PubMedID- 23057723 Case presentation: a 74-year-old caucasian woman showed a sporadic creutzfeldt-jakob disease clinical phenotype with reactive depression, followed by cognitive impairment, akinetic-rigid parkinsonism with pseudobulbar syndrome and gait impairment with motor apraxia, visuospatial disorientation, and evident frontal dysfunction features such as grasping, palmomental reflex and brisk perioral reflexes.

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