PedAM
Pediatric Disease Annotations & Medicines
| Disease | mental depression |
| Phenotype | C0014544|epilepsy |
| Sentences | 61 |
| PubMedID- 22957244 | Anhedonia has also been proposed as a better marker for depression in patients with epilepsy, in part secondary to its independence from physical symptoms associated with medications and chronic illness [32]. |
| PubMedID- 25807125 | In adolescents with epilepsy, high scores of anxiety and depression are associated with occurrence of seizures in public places. |
| PubMedID- 26284748 | There is a high prevalence of depression in patients with epilepsy, which negatively impacts their quality of life (qol) and seizure control. |
| PubMedID- 25597526 | Primary study aims included the examination of 1) rates of self-reported depression in youth with epilepsy, 2) differences in depression by demographic and medical variables, 3) the impact of depression on hrqol, and 4) changes in depression and suicidal ideation following a behavioral medicine consultation. |
| PubMedID- 21742562 | The aims were to examine the process of gp screening for depression in patients with epilepsy employing the widely used patient health questionnaire-2 (phq-2) and the nddi-e; to determine the impact of screening on gp-recognized depression; and to ascertain depression predictors. |
| PubMedID- 22162974 | We then show that depression in epilepsy provides a perfect model for the biopsychosocial etiology of depression and discuss related therapeutic approaches. |
| PubMedID- 24138845 | Despite substantial research into mood disorders, depression associated with epilepsy has received insufficient attention. |
| PubMedID- 20888306 | depression in epilepsy is associated with lack of seizure control. |
| PubMedID- 23520221 | Aims: to examine the efficacy of bright light therapy for symptoms of anxiety and depression in adults with focal epilepsy (trial registration at clinicaltrials.gov: nct01028456). |
| PubMedID- 22681163 | The prevalence of depression in patients with epilepsy (pwe) is high. |
| PubMedID- 23394027 | Comorbid depression in epilepsy affects negatively the health-related quality of life, increases suicide risk and costs of medical care when compared to patients without depression selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitor are first-line treatment of depression in patients with epilepsy. |
| PubMedID- 21093520 | The wag/rij strain: a genetic animal model of absence epilepsy with comorbidity of depression [corrected]. |
| PubMedID- 24681386 | Screening for depression in people with epilepsy: comparative study among neurological disorders depression inventory for epilepsy (nddi-e), hospital anxiety and depression scale depression subscale (hads-d), and beck depression inventory (bdi). |
| PubMedID- 24069608 | We have recently shown increased mossy fiber sprouting in patients with epilepsy and history of major depression and decreased in epilepsy with interictal psychosis, which may indicate a morphological basis for psychiatric symptoms in mtle [11]. |
| PubMedID- 26076841 | Purpose: the comorbidity of depression in patients with epilepsy is common and treatment is still controversial. |
| PubMedID- 26368332 | Clinical data demonstrate a 30–35% lifetime prevalence of depression in patients with epilepsy, and patients diagnosed with depression have a three to sevenfold higher risk of developing epilepsy. |
| PubMedID- 24912293 | For example, interictal depression in individuals with epilepsy is more prevalent than in the general population or among patients with other chronic disorders. |
| PubMedID- 22934159 | A number of researches have reported the comorbidity of anxiety along with depression in patients with epilepsy [20–22]. |
| PubMedID- 26576071 | To the best of our knowledge, our study is the first study that has attempted to compare the frequencies of both depression and anxiety in patients with epilepsy to another chronic brain disorders, in this case, ms. previous studies have compared the rates of depression to other chronic medical conditions. |
| PubMedID- 20851689 | Further education of community physicians and neurologists regarding the importance of treating depression in patients with epilepsy and research into the use of antidepressants in this population are indicated. |
| PubMedID- 23591757 | Mood disorders represent a frequently encountered comorbidity in epilepsy, but the issue of phenomenology of depression is still matter of debate, having relevant implications in terms of treatment and prognosis. |
| PubMedID- 23594674 | Pre-existing depression among patients with new-onset epilepsy is up to seven times more common than in a control population (reviewed in kanner[14]). |
| PubMedID- 25597527 | Objective: depression in people with epilepsy (pwe) is underdiagnosed and undertreated. |
| PubMedID- 22050514 | Purpose: memory deficits and depression are common in patients with temporal lobe epilepsy (tle). |
| PubMedID- 24074883 | Conclusion: symptoms of depression were associated with epilepsy both during and before pregnancy. |
| PubMedID- 22871254 | Subjects completed the state and trait anxiety inventory and the beck depression inventory; patients with epilepsy also completed the epilepsy foundation concerns index. |
| PubMedID- PMC3943350 | The second speaker will focus on the biopsychosocial model of depression in epilepsy with special emphasis on the similarities between the two disorders with respect to genetic predisposition, neurotransmitters, and stress. |
| PubMedID- 22787593 | Some of the clinical features of depression in patients with epilepsy suggest a neurobiological connection, although it is difficult to eliminate psychosocial and iatrogenic factors in human studies. |
| PubMedID- 21725390 | Results: diagnosing depression in patients with epilepsy may be difficult, because the symptoms are somewhat atypical and appear episodically. |
| PubMedID- 23209983 | This finding is similar to earlier findings from west africa which showed that age, gender, and living environment did not significantly influence depression among patients with epilepsy even though higher frequency of depression was found in females. |
| PubMedID- 23233847 | Adult epilepsy patients with depression, anxiety disorders, and sub-syndromic depression have significantly higher aed adverse effect profiles than those without these diagnoses (kanner et al., 2012). |
| PubMedID- 22632407 | The clinical manifestations of depression in people with epilepsy (pwe) are pleomorphic, often associated with anxiety symptoms and anxiety disorders. |
| PubMedID- 22099527 | depression in patients with temporal lobe epilepsy (tle) is highly prevalent and carries significant morbidity and mortality. |
| PubMedID- 24863509 | The relationship between sleep quality, depression, and anxiety in patients with epilepsy and suicidal ideation. |
| PubMedID- 22737444 | The prevalence of depression and anxiety in patients with epilepsy, with and without other chronic somatic illnesses was not significantly different. |
| PubMedID- 21701630 | The prevalence of depression in epilepsy patients ranges from 20%–55%28 and psychosis has been reported in 6%–9%.29 these rates are significantly higher than those seen in the general population. |
| PubMedID- 23175727 | Conclusions: epilepsy was significantly associated with depression and depression was observed to be highly prevalent in pwe. |
| PubMedID- 25082253 | Aim: to compare the levels of anxiety and depression in patients with milder epilepsy characterized by complex partial seizures versus more severe epilepsy comprised of generalized tonic-clonic seizures. |
| PubMedID- 26033229 | The present study examined anxiety and depression in adolescents with epilepsy and the association of these disorders with seizure-related and sociodemographic variables. |
| PubMedID- 24657500 | Determinants of depression among patients with epilepsy in athens, greece. |
| PubMedID- 25889039 | We have previously reported neuropathological alterations in mesial temporal lobe epilepsy (mtle) patients with major depression and psychosis that suggest a morphological and neurochemical basis for psychopathological symptoms. |
| PubMedID- 24167947 | The purpose of this article is to review strategies used in the pharmacologic treatment of depression in patients with epilepsy, choice of antidepressants, effects of antidepressants on seizure threshold, pharmacokinetic interactions between antidepressant drugs and antiepileptic drugs and psychotropic properties of antiepileptic drugs. |
| PubMedID- 26481533 | Background: the incidence rate of depression among patients with epilepsy is relatively high. |
| PubMedID- 21750525 | depression in epilepsy can be described in the general framework of the diathesis-stress model: chronic stress exposure owing to the 'burden of epilepsy' and learned helplessness due to the threat of recurrent seizures as unpredictable aversive events represent psychological risk factors for the development of depression. |
| PubMedID- 24341899 | Therefore, common pathogenic mechanisms may be involved in the etiology of depression comorbid with different epilepsy syndromes, and we would expect that this should be demonstrable in patients having different clinical characteristics of epilepsy, such as those included in the current study. |
| PubMedID- 26491329 | Patients with focal epilepsy were diagnosed with depression more often (n=61, [32.3%]) than those with generalized epilepsy (n=12 [19.0%], p=0.045). |
| PubMedID- 22766393 | Wag/rij rats represent a validated genetic animal model of absence epilepsy with mild-depression comorbidity, also including other behavioral alterations. |
| PubMedID- 20858043 | Hypoactivity was consistently found in the frontal cortex and temporal region in temporal lobe epilepsy (with and without depression). |
| PubMedID- 22018800 | Objective: the aim of the work described here was to measure the role of psychopathological features, specifically impulsivity and depression, in suicidality in patients with temporal lobe epilepsy (tle). |
| PubMedID- 23673289 | depression in patients with newly diagnosed epilepsy predicts lamotrigine-induced rash: a short-term observational study. |
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