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PedAM

Pediatric Disease Annotations & Medicines




Disease malnutrition
Phenotype C0023890|cirrhosis
Sentences 19
PubMedID- 25974421 malnutrition in cirrhosis increases morbidity and mortality.
PubMedID- 26036456 The patient had a past history of liver cirrhosis hcv-related with a severe malnutrition, hypertrophic cardiomyopathy, diverticular disease, hiatal ernia, previous appendectomy.
PubMedID- 23936183 Bcaa has been used as a supplemental therapy to improve malnutrition in patients with liver cirrhosis [1].
PubMedID- 24273224 Supplementation with branched-chain amino acids (bcaa), which are used to improve protein malnutrition in patients with liver cirrhosis, can also reduce the risk of hcc in obese cirrhotic patients.
PubMedID- 21422706 Energy malnutrition worsens survival in patients with liver cirrhosis, and is currently defined as non-protein respiratory quotient (nprq) <0.85, as measured by indirect calorimetry.
PubMedID- 21284673 malnutrition also occurs in patients with cirrhosis due to etiologies other than alcohol.
PubMedID- 23722148 Anasarca and malnutrition associated with cirrhosis predispose to poor wound-healing and soft tissue infection (4).
PubMedID- 25789501 We found that supplementation with branched-chain amino acids (bcaa), which improve protein malnutrition in patients with liver cirrhosis [38], significantly inhibited liver carcinogen diethylnitrosamine (den)-induced hepatocarcinogenesis as well as spontaneously occurring hepatic preneoplastic lesions in db/db obese and diabetic mice [34,39].
PubMedID- 21518402 Conclusion: les with bcaa-enriched nutrient therapy can improve protein malnutrition in patients with liver cirrhosis, and is more useful in the early stages of liver cirrhosis in improving hepatic parenchymal cell mass.
PubMedID- 23874070 Moreover, patients with an acceptable nutritional status have a poor la and lc-pufa status, while malnutrition associated with cirrhosis leads to lower levels of n-6 and n-3 pufa in patients with alcoholic liver cirrhosis.
PubMedID- 20576106 Most of the data on malnutrition in patients with cirrhosis have been derived from western patients in whom chronic alcohol ingestion has been the commonest aetiology.
PubMedID- 26155840 Underlying cirrhosis frequently leads to protein-calorie malnutrition commonly caused by poor appetite, cacochylia, compromised nutrient uptake, and disorders in protein synthesis [9, 10].
PubMedID- 23101983 malnutrition among patients with cirrhosis or alcoholic liver disease correlates with poor quality of life, increased risk of infections, frequent hospitalizations, complications, mortality, poor graft and patient survival after liver transplantation, and economic burden.
PubMedID- 23027617 Branched-chain amino acids (bcaa), which improve protein malnutrition in patients with liver cirrhosis, reduce the risk of hepatocellular carcinoma in these patients with obesity.
PubMedID- 24665321 The prevalence of malnutrition in cirrhosis may be as high as 100%.
PubMedID- 25190687 malnutrition was associated with cirrhosis (prevalence ratio [pr], 1.25; 95% confidence interval [ci], 1.1-1.4; p < .001), alcohol abuse, direct bilirubin >3.0 mg/dl, international normalized ratio >1.1, platelet <150 x 10(3)/mm(3), hemoglobin <12 g/dl, and serum albumin <3.5 g/dl (p < .05).
PubMedID- 22969221 The effect of malnutrition on survival in patients with decompensated liver cirrhosis has not been well defined.
PubMedID- 23304537 A variety of mechanisms are considered to contribute to malnutrition in cirrhosis such as poor food intake, malabsorption, increased intestinal protein loss, decreased protein synthesis, disturbances in substrate utilization, and hypermetabolism.
PubMedID- 24160225 Introduction: since malnutrition is common in patients with hepatic cirrhosis (hc) is necessary to investigate the interference of the pathophysiological changes of liver in the methods of diagnosis of the nutritional status.

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