PedAM
Pediatric Disease Annotations & Medicines
| Disease | malaria |
| Phenotype | C0019045|haemoglobinopathies |
| Sentences | 4 |
| PubMedID- 22445352 | Methods: we systematically searched the medline and embase databases for studies that estimated the risk of malaria in patients with and without haemoglobinopathies up to sept 9, 2011, and identified additional studies from reference lists. |
| PubMedID- 22549448 | Measurement of th1, th2 cytokines and white cell count in childhood haemoglobinopathies with uncomplicated malaria infection. |
| PubMedID- 22561610 | Similarly, host attributes including the assorted haemoglobinopathies reduce the likelihood of severe malaria, but even amongst similar individuals some die and others do not. |
| PubMedID- 20128890 | The observed overlaps in the geographic distributions of malaria with the haemoglobinopathies, particularly hbs [5-7], have been cited in support of the hypothesis that malaria has been an important evolutionary force in selection of this and other variants, with evidence for genome-shaping interactions found in the geographic and ethnic distributions across the globe [8]. |
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