PedAM
Pediatric Disease Annotations & Medicines
| Disease | malaria |
| Phenotype | C0002871|anaemia |
| Sentences | 71 |
| PubMedID- 26464799 | Sickle cell disease and malaria were significantly associated with severe anaemia in this study. |
| PubMedID- 23473847 | However, results from studies in adults might not generalise to children who have different comorbidities (eg, more anaemia associated with malnutrition, malaria, and sepsis, which could affect haematological monitoring). |
| PubMedID- 25889709 | It is estimated that approximately 500,000 pregnant women develop severe anaemia due to falciparum malaria [31,32] and up to 10,000 maternal anaemia-related deaths are as a result of malaria infection in sub-saharan africa [33,34]. |
| PubMedID- 20359364 | anaemia in malaria can be associated with more pathogenetic mechanisms, such as haemolysis and dyserythropoiesis. |
| PubMedID- 20808923 | The unit costs of an inpatient or outpatient visit for malaria with or without anaemia are presented in table 3. |
| PubMedID- 22479564 | Among anaemic children in malawi who were transfused for severe anaemia, 64% of them had malaria parasitaemia. |
| PubMedID- 23057857 | In a logistic regression analysis, anaemia was significantly associated with malaria parasitaemia (aor=5.23, 95%ci[1.1-28.48]), sickle cell disorders (aor=2.89, 95%ci[1,32-6.34]), alpha-thalassemia (aor=1.82, 95%ci[1.2-3.35]), stunting (aor=3.37, 95%ci[1.93-5.88], age ranged from 2 to 4 years (aor=0.13, 95%ci[0.05-0.31]) and age > 5 years (aor=0.03, 95%ci[0.01-0.08]). |
| PubMedID- 23762446 | This can explain the conflicting results obtained in sub-saharan africa, on the relationship between pam and anaemia and the inconsistency of the influence of malaria infection on haemoglobin concentration and anaemia in our study [3]. |
| PubMedID- 21687688 | In doing so, we adjust for malnutrition and the prevalence of infection of the major parasitic contributors and estimate the attributable risk of anaemia due to malnutrition, malaria, and helminth infections. |
| PubMedID- 23226937 | Asymptomatic malaria correlates with anaemia in pregnant women at ouagadougou, burkina faso. |
| PubMedID- 26502714 | The anaemia associated with falciparum malaria is multifactorial and is thought to be due to greater destruction of unparasitized red blood cells compared to parasitized red blood cells, and bone marrow dyserythropoiesis of variable intensity and duration [16–18, 37–39]. |
| PubMedID- 25410687 | A final diagnosis of haemophagocytic lymphohistiocytosis (hlh) with megaloblastic anaemia associated with severe mixed malaria was made. |
| PubMedID- 24194926 | anaemia was independently associated with infections including malaria (or 3.49, 95% ci 1.78-6.82), hiv (or 2.17, 1.32-3.57) heavy hookworm infection (or 3.45, 1.73-6.91), low fruit consumption (or 1.55, 1.05-2.29) and being unmarried (or 1.37 , 95% ci 1.01-1.89). |
| PubMedID- 26101076 | Among both fortification and non-fortification countries, hdi and malaria were significantly associated with anaemia (p,0.001). |
| PubMedID- 20712868 | Monocyte icam-1 levels are higher in cerebral malaria patients compared with severe malaria anaemia patients. |
| PubMedID- 22708041 | Severe malaria is associated with development of anaemia, usually normochromic and normocytic. |
| PubMedID- 23970747 | We did not test for malaria or underlying causes of anaemia, but recorded any diagnosis already documented. |
| PubMedID- 21304925 | It is likely that the fraction of anaemia attributable to malaria differs between settings and this fraction is likely to be lower in areas with lower transmission intensity such as senegal. |
| PubMedID- 22548983 | Nevertheless, malaria infection is associated with severe maternal anaemia, placental malaria and low birth weight – a risk factor for infant death [6,7]. |
| PubMedID- 26542672 | After adjusting for all predictors, anaemia risk was associated with malaria parasitaemia, age group, hh ses and underweight, with a borderline significant outcome noted among children with stunting and those coming from hhs where irs was applied. |
| PubMedID- 21819616 | Since our previous investigations in this region demonstrated that hiv-1 status [27] and bacterial co-infection [28] enhance the development of anaemia in children with malaria, all study participants were tested for these co-pathogens (testing methods listed below). |
| PubMedID- 26537247 | None of age, pregnancy status, parity, or anaemia were associated with malaria infection in univariate or multivariate analyses (table 2). |
| PubMedID- 25889165 | The pathogenesis of severe anaemia in vivax-malaria remains unclear and is likely caused by multiple underlying factors. |
| PubMedID- 21262115 | Vivax malaria with auto-immune haemolytic anaemia (aiha) was diagnosed. |
| PubMedID- 24761799 | anaemia associated with malaria is caused by hemolysis of the red blood cells and hypersplenism, a condition characterized by the exaggeration of inhibitory or destructive function of the spleen [15]. |
| PubMedID- 23205261 | malaria complications result from haemolytic anaemia and microvascular obstruction with subsequent tissue ischemia. |
| PubMedID- 24217041 | The anaemia was due to malaria (48.2%), helminthiasis (22.2%), malnutrition (14.8%), and sickle cell disease (14.8%). |
| PubMedID- 24489732 | The prevalence of anaemia was significantly associated with malaria infection (χ2 = 15.58, p<0.001) and s. haematobium infection (χ2 = 16.34, p<0.001). |
| PubMedID- 22073155 | The population attributable proportion of anaemia (hb≤8.0 g/dl) due to malaria was low but was about three times higher in the health centre (15.6%) than in the community (5.4%) surveys in the wet season. |
| PubMedID- 26032157 | All her symptoms (especially high parasitaemia and strong anaemia) are characteristics of a strong malaria attack in a naïve individual. |
| PubMedID- 20433718 | Adults usually have some level of parasites in them that do not necessarily cause clinical malaria but can lead to anaemia and its related complications. |
| PubMedID- 22540175 | In these regions, vivax malaria is commonly associated with severe anaemia both in the health care and community setting. |
| PubMedID- 22484763 | Furthermore, there are a number of causes of anaemia in malaria endemic areas, and whilst persistent malaria infection is a major factor there are other important contributory causes including co-infections with hiv-1 (davenport et al., 2010), and malnutrition. |
| PubMedID- 21687687 | The authors attempt to partly address this challenge by computing the anaemia paf of malnutrition, malaria, and helminth infections. |
| PubMedID- 22624872 | In vivax malaria patients with anaemia red cells in blood film are usually normochromic and normocytic with the absolute reticulocyte count not elevated [15]. |
| PubMedID- 24490093 | Unusual presentation of vivax malaria with anaemia, thrombocytopenia, jaundice, renal disturbance, and melena: a report from malang, a nonendemic area in indonesia. |
| PubMedID- 20500831 | The high prevalence of anaemia in malaria patients of the underweight status groups than those in the normal weight and overweight groups suggests malnutrition as a risk factor for anaemia besides malaria and helminth infections. |
| PubMedID- 24522135 | The difference in levels of tnf alpha was significantly higher in falciparum malaria patients with anaemia, altered liver functions, hyperparasitemia, leucocytosis, hepatosplenomegaly and hypoglycaemia. |
| PubMedID- 22835018 | Remarkably, anaemia was significantly associated with hiv-infection in malaria patients, and a trend towards a lower platelet number was also observed in co-infected individuals. |
| PubMedID- 22429464 | Overall prevalence of maternal malaria was 52%, associated with younger age, anaemia and smaller infant birth size. |
| PubMedID- 26169783 | Lbw and severe maternal anaemia are associated with frequent malaria episodes and the timing of infections [16], and it is likely that the reduction in these outcomes is due in part at least, to a reduction in the risk of recurrent malaria. |
| PubMedID- 24598692 | Specifically, the children most vulnerable to anaemia – those with malaria – were less anaemic post-intervention in all three countries, suggesting they were more robust and less prone to the risk of complications or death associated with malaria. |
| PubMedID- 23978045 | Even though tnf and il-10 are thought to contribute to the degree of anaemia in children with falciparum malaria, no significant difference was observed among the mice strains in this study, and even when compared with uninfected control. |
| PubMedID- 26541669 | Malnutrition enhanced the severity of anaemia in malaria parasite negative children hence, their health and growth potential needs to be improved upon. |
| PubMedID- 21867566 | Poor maternal and perinatal outcomes in cases of anaemia associated with malaria have recently been documented in some regions of sudan including kassala [19]. |
| PubMedID- 20559558 | Although not part of this analysis, if we were to add the benefits of the additional health gains and subsequent cost savings from averting anaemia and those associated with averting the non-malaria admissions included in ‘all-cause’ hospitalisations (here we included only hospital admissions with parasitaemia), the icers would be even more cost effective. |
| PubMedID- 23553281 | To the best of our knowledge, this is the second reported case of a patient affected by severe falciparum malaria with haemolytic anaemia that is likely associated with oral artemether-lumefantrine treatment. |
| PubMedID- 21529344 | Moreover, malaria often leads to severe anaemia in pregnant african women [10]. |
| PubMedID- 23465781 | Recent work in young ugandan children has found that anaemia is mostly attributable to malaria rather than intestinal schistosomiasis [44]. |
| PubMedID- 23587107 | Severe anaemia attributable to severe malaria contributed considerably to the near miss burden in this study. |
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