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PedAM

Pediatric Disease Annotations & Medicines




Disease malabsorption syndrome
Phenotype C0011991|diarrhea
Sentences 26
PubMedID- 22685452 Three major mechanisms have been proposed for the diarrhea seen with cryptosporidiosis: 1) malabsorption resulting in an osmotic diarrhea; 2) parasite-induced generation of inflammatory products and host neurohumoral secretogogues; 3) secretory diarrhea resulting from a parasite enterotoxin.
PubMedID- 25072743 The predominant consequence of cd is malnutrition due to malabsorption (with diarrhea, weight loss, nutritional deficiencies, and altered blood parameters), especially in patients who do not show strict adherence to gfd treatment.
PubMedID- 22605972 In the absence of carbohydrate malabsorption in a patient with osmotic diarrhea, it is essential to determine if steatorrhea is present.
PubMedID- 26210192 Afferent loop syndrome should be suspected in case of malabsorption syndrome with chronic diarrhea, steatorrhea, iron-deficiency anemia, edema, emaciation, and osteomalacia and also in case of simple biological anomalies such as macrocytosis or megaloblastic anemia.
PubMedID- 23759075 The former increases susceptibility to infection, morbidity and mortality through opportunistic infections, fever, diarrhea, loss of appetite, nutrient malabsorption, and weight loss [1-3].
PubMedID- 20485260 This small intestinal mucosal disorder is gluten-dependent and causes nutrient malabsorption, often with diarrhea and weight loss.
PubMedID- 22765392 Background: many physicians do not consider the diagnosis of bile acid malabsorption in patients with chronic diarrhea, or do not have access to testing.
PubMedID- 20932141 Chronic diarrhea due to bile acid malabsorption may be considered as contributing to the diagnosis when it results from secondary causes, such as ileal resection affecting the enterohepatic circulation.
PubMedID- 24339463 Cryptosporidiosis causes severe chronic and even fatal diarrhea with malabsorption and dehydration.
PubMedID- 23028934 Further, anion hypersecretion [44], increased intestinal transit rates due to mast cell degranulation [45], brush border shortening due to activation of lymphocytes [40], maldigestion due to brush border enzyme deficiencies [28] and small intestinal malabsorption [36] are causes of diarrhea in giardiasis [41], [46].
PubMedID- 24505462 We supposed that cr-induced diarrhea leads to intestinal malabsorption of carbohydrates or fats, furthermore results in energy deficiency and energy metabolism disorder.
PubMedID- 23617890 However, even after a careful consideration of various causes of diarrhea associated with malabsorption, it was not possible to identify a cause that could confirm the suspected diagnosis.
PubMedID- 22355316 Persons with this disorder have severe, life-threatening diarrhea due to hexose malabsorption [3], [7].
PubMedID- 23264789 [5] the classic presentation of severe malabsorption syndrome with chronic diarrhea, steatorrhea, and weight loss, however, is less common in cd that is known as the “iceberg” condition.
PubMedID- 23119161 Around 50% of giardia infections are asymptomatic, in others the major symptoms of giardia infection include diarrhea, with malabsorption, dehydration, weight loss, cognitive impairment in children, and chronic fatigue in adults as well as other symptoms [2].
PubMedID- 20920215 The diagnosis is based on a history of chronic diarrhea with fat malabsorption and abnormal lipid profile.
PubMedID- 20701796 Our group has demonstrated that intestinal epithelial barrier breakdown due to enteric infections and diarrhea might lead to antiretroviral drug malabsorption and increased drug resistance [11].
PubMedID- 22545042 These results indicate that classic presentation of malabsorption, specially with chronic diarrhea, is the main presentation of cd in our society.
PubMedID- 21838873 diarrhea, sometimes accompanied with malabsorption, steatorrhea, and crampy abdominal pain, is a frequent complaint in md patients [6].
PubMedID- 23984314 Celiac disease (cd) is a chronic immune-mediated disorder triggered by the ingestion of gluten that appears in genetically predisposed patients the clinical spectrum of cd is wide and includes classic presentation of malabsorption with diarrhea, nonclassical extraintestinal features, subclinical or asymptomatic forms, and potential disease characterized by positive serology with a normal intestinal mucosa on biopsy [1, 2].
PubMedID- 20599999 The symptoms of giardiasis include abdominal cramps, nausea, and acute or chronic diarrhea, with malabsorption and failure of children to thrive occurring in both sub-clinical and symptomatic disease (thompson et al., 1993).
PubMedID- 20416046 Cow's milk-sensitive enteropathy may present with malabsorption leading to diarrhea and failure to thrive.
PubMedID- 23091702 Enterocytozoon bieneusi can be an important cause of persistent diarrhea, intestinal malabsorption, and wasting in hiv-positive adults.
PubMedID- 25073040 Severe and chronic posttransplant diarrhea may lead to dehydration, malabsorption, rehospitalization, immunosuppression, noncompliance, and a greater risk of graft loss and death.
PubMedID- 22545223 The classic presentation of cd is a severe malabsorption syndrome with diarrhea, steatorrhea, and weight loss and possess antibodies against gliadin and especially tissue transglutaminase [2].
PubMedID- 23056761 Some patients present as young children with classical cd and severe malabsorption leading to diarrhea, abdominal distention, growth failure and general malaise[1].

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