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PedAM

Pediatric Disease Annotations & Medicines




Disease lymphoma
Phenotype C0085110|severe combined immunodefic
Sentences 3
PubMedID- 20501616 In a severe combined immunodeficient-beige mouse model of transformed cutaneous t-cell lymphoma, the addition of pralatrexate to bortezomib enhanced efficacy compared with either drug alone.
PubMedID- 25072059 In a severe combined immunodeficiency (scid) mouse model of disseminated residual lymphoma, anti-cd20-rli was found to induce long-term survival of 90% of mice up to at least 120 days whereas rli and rtx, alone or in combination, just delayed the disease onset (100% of death at 28, 40 and 51 days respectively).
PubMedID- 22150234 In an in vivo severe combined immunodeficiency mouse model of human lymphoma, ofatumumab prolonged median survival compared to rituximab.

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