PedAM
Pediatric Disease Annotations & Medicines
| Disease | lymphoma |
| Phenotype | C0019204|hepatocellular carcinoma |
| Sentences | 1 |
| PubMedID- 22754758 | Thus, occasionally, distant metastases, which have not been irradiated, exhibit a delayed therapeutic response, as this has been documented for example for melanoma,2 lymphoma,3 adenocarcinoma,4 hepatocellular carcinoma5 or merkel cell carcinoma.6 clinicians initially attempted to explain the abscopal effect by a radiation-induced increase in the circulating levels of cytokines such as tumor necrosis factor5 or interleukin-18.7 however, recent evidence suggests that local radiotherapy can elicit an immune response whose effectors, most likely t lymphocytes, then migrate to distant lesions provoking their regression. |
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