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PedAM

Pediatric Disease Annotations & Medicines




Disease lymphoid leukemia
Phenotype C0023470|myelogenous leukemia
Sentences 3
PubMedID- 23989717 Major successes have been largely restricted to agents targeting human epidermal growth factor receptor-2 (mutated or overexpressed in breast cancer), bcr-abl (chronic myelogenous leukemia and some cases of acute lymphoblastic leukemia), and c-kit (gastrointestinal stromal tumor).
PubMedID- 25332597 Philadelphia (ph) chromosome is most commonly associated with chronic myelogenous leukemia (cml), a subset of precursor b-cell acute lymphoblastic leukemia and acute biphenotypic leukemia.
PubMedID- 25949834 The philadelphia chromosome (ph), t(9;22)(q34;q11.2), is consistently seen in chronic myelogenous leukemia (cml), 25% of adult b-acute lymphoblastic leukemia (b-all), 2–4% of childhood b-all, and rarely in acute myeloid leukemias [1].

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