PedAM
Pediatric Disease Annotations & Medicines
| Disease | lupus |
| Phenotype | C0149530|congenital heart block |
| Sentences | 3 |
| PubMedID- 23910804 | Complete congenital heart block (cchb) accompanied with neonatal lupus erythematosus is caused by an immune reaction between maternal anti-ro/ssa antibodies and the fetal heart and is generally considered an irreversible process. |
| PubMedID- 25545844 | While current strategies are able to achieve live births in 85-90% of pregnancies, certain aspects such as prevention of preterm birth, treatment of congenital heart block due to neonatal lupus and recurrent pregnancy loss despite best management, remains challenging. |
| PubMedID- 21618202 | Objective: congenital heart block (chb), a manifestation of neonatal lupus, is associated with maternal anti-ro/ssa and anti-la/ssb autoantibodies and recurs in approximately 18% of subsequent pregnancies. |
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