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PedAM

Pediatric Disease Annotations & Medicines




Disease lupus
Phenotype C0040034|thrombocytopenia
Sentences 24
PubMedID- 25117655 We investigated the relationship between tpo and the occurrence of thrombocytopenia and thrombosis in patients with systemic lupus erythematosus (sle).
PubMedID- 26090044 [acquired amegakaryocytic thrombocytopenia purpura: think of systemic lupus erythematosus].
PubMedID- 24744634 Rituximab therapy for refractory autoimmune thrombocytopenia in patients with systemic lupus erythematosus.
PubMedID- 19885662 Since the role of splenectomy in treating thrombocytopenia associated with systemic lupus erythematosus has been controversial, the study was focused on determining the efficacy of splenectomy in the sle-associated thrombocytopenia.
PubMedID- 21571767 Low-dose rituximab therapy for refractory thrombocytopenia in patients with systemic lupus erythematosus--a prospective pilot study.
PubMedID- 21326158 Successful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (sle).
PubMedID- 21776377 A case of thrombotic thrombocytopenia purpura associated with systemic lupus erythematosus: diagnostic utility of adamts-13 activity.
PubMedID- 21794686 [treatment with rituximab for thrombocytopenia due to systemic lupus erythematosus].
PubMedID- 20433308 The purpose of this investigation was to determine the characteristics of the clinical manifestations, laboratory findings and prognostic impact of the thrombocytopenia patients with systemic lupus erythematosus (sle).
PubMedID- 21371350 Intravenous immunoglobulin (ivig) has been reported to successfully treat severe thrombocytopenia associated with neonatal lupus [55], but ivig does not prevent recurrence of chb [56].
PubMedID- 24740463 There are very few reports on the use of eltrombopag in patients with thrombocytopenia associated with sytemic lupus.we present a recent case of a patient with lupus with severe thrombocytopenia refractory to conventional therapy and full recovery with the use of eltrombopag.
PubMedID- 24811320 One subject died due to severe cmv infection and one due to massive central nervous system bleeding, secondary to severe thrombocytopenia associated with systemic lupus erythematosus.
PubMedID- 23549638 This study aims to investigate the efficacy and safety of laparoscopic splenectomy (ls) in the management of refractory thrombocytopenia associated with systemic lupus erythematosus (sle).
PubMedID- 21729561 This study was purposed to investigate the mechanism of thrombocytopenia in patients with systemic lupus erythematosus (sle) through detecting anti-megakaryocyte antibodies in sle patients.
PubMedID- 25818822 Leukopenia and lymphocytopenia are correlated and leukopenia is more common in systemic lupus erythematosus patients with psychosis, thrombocytopenia and anti-double stranded dna.
PubMedID- 26024588 Thrombopoietin- receptor agonist as a treatment of thrombocytopenia associated with systemic lupus erythematosus.
PubMedID- 23161579 We report here a preterm case of neonatal lupus with thrombocytopenia and comorbid hemorrhagic stroke.
PubMedID- 20376666 Although this life-threatening event is rare in paediatrics, the presence of lupus anticoagulant combined with previously asymptomatic thrombocytopenia allowed a diagnosis of systemic lupus erythematosus (sle).
PubMedID- 20937127 Subjects were excluded from participation if they had (1) a known allergy to minocycline or tetracycline, (2) kidney disease or elevated renal function tests, (3) liver disease or elevated liver function tests, (4) neutropenia, anemia, or thrombocytopenia, (5) history of systemic lupus erythematosus or screening anti-nuclear antibody (ana) titre of > 1:40, as minocycline may cause a lupus-like reaction, (6) individuals who did not have a parent or caregiver who was willing to participate in the clinic visits, (7) individuals who were pregnant or at risk of becoming pregnant, specifically sexually active females were excluded.
PubMedID- 23128336 We present a young patient with thrombocytopenia as a result of neonatal lupus, a passively acquired autoimmune disease.
PubMedID- 26266073 In summary, this previously healthy young lady presented with acute vision changes and stroke like symptoms and was diagnosed with sle, which was attributed to the following findings: thrombocytopenia, significant elevation of inflammatory markers, positive lupus serologies, and lupus anticoagulant antibodies.
PubMedID- 22131818 90% of lupus patients with thrombocytopenia have been shown to possess antibodies directed against either the glycoprotein iib/iiia or thrombopoietin receptor [29].
PubMedID- 20064913 We also found that the systemic lupus erythematosus patients with thrombocytopenia have a lower frequency of socs1-1478del compared with patients without thrombocytopenia.
PubMedID- 26000103 Antiphospholipid syndrome (aps) is characterized by recurrent venous or arterial thromboses, fetal losses and thrombocytopenia in the presence of antiphospholipid antibodies, namely lupus anticoagulant, anticardiolipin antibodies or antibodies directed to various proteins, mainly beta2 glycoprotein i, or all three.

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