PedAM
Pediatric Disease Annotations & Medicines
| Disease | lupus |
| Phenotype | C0017658|glomerulonephritis |
| Sentences | 31 |
| PubMedID- 20886026 | Recently, harroche described a case of pulmonary embolism revealing a systemic lupus erythematosus with membranous glomerulonephritis in a 14-year-old boy [14]. |
| PubMedID- 23717217 | In mouse models of lupus with associated glomerulonephritis, ibrutinib produced a significant reduction in proteinuria, blood urea nitrogen, and anti-double-stranded dna levels. |
| PubMedID- 26251707 | Different autoimmune diseases such as vasculitis and systemic lupus erythematosus are associated with glomerulonephritis (gn) causing aki (table 4). |
| PubMedID- 26557026 | B cell activating factor-transgenic mice harbor increased b220+ b cells and plasma cells in the spleen and lymph nodes, and develop antidouble-stranded dna antibodies, proteinuria, and glomerulonephritis consistent with a systemic lupus erythematosus-like autoimmunity as they age [20]. |
| PubMedID- 20827419 | [15] showed for the first time that not only th1, but also th17 effector t cells mediate glomerulonephritis in lupus model mrl/lpr mice. |
| PubMedID- 22640266 | They included 10 inactive glomerulonephritis patients due to systemic lupus erythromatosus (sle) (group i), 10 renal transplantation cases (group ii) and 10 patients of other aetiologies as the control group. |
| PubMedID- 21855148 | Various studies indicate a role for both anti-nucleosome and anti-c1q autoantibodies in glomerulonephritis in patients with systemic lupus erythematosus. |
| PubMedID- 25632350 | Our data support april as a candidate biomarker of renal disease activity in lupus patients with proliferative glomerulonephritis and point to low baseline blys levels predicting treatment response in ln, especially in pln. |
| PubMedID- 24860805 | Mice deficient for pd-1 have developed a lupus-like syndrome, with arthritis and glomerulonephritis as phenotypes [19]. |
| PubMedID- 25890083 | As typically seen in sle, scurfy mice developed mesangioproliferative glomerulonephritis meeting the criteria of who class ii lupus nephritis, which may have been overlooked in previous analysis if sections were not specifically stained with pas or by if [42]. |
| PubMedID- 23056220 | In addition, 2-cda exhibits various other effects on immune system and therefore it was explored for therapeutic utility in autoimmune disorders such as glomerulonephritis associated with systemic lupus erythematosus, rheumatoid arthritis and refractory celiac disease [19]–[21]. |
| PubMedID- 22162633 | In addition to the aforementioned studies associating type i ifn and clinical and serological features of sle, cdna microarray analysis of gene expression in glomeruli, isolated by laser-capture microscopy from kidney biopsies of lupus patients with focal/diffuse proliferative glomerulonephritis, revealed increased expression of type i ifn-inducible genes, thus, implying a possible pathogenetic role for type i ifn in these patients [17]. |
| PubMedID- 22470397 | This issue has also been highlighted in a study showing that the use of pcr to estimate 24-hour protein excretion leads to significant numbers of false-positive and false-negative diagnoses of glomerulonephritis flares in patients with systemic lupus erythematosus [12]. |
| PubMedID- 23844121 | For example, the presence of a cnv in the fcgr3b gene has been linked to the development of glomerulonephritis in patients with systemic lupus erythematosus [16,17]. |
| PubMedID- 23052657 | Demonstrated that tsa decreased proteinuria and the proliferative hallmarks of glomerulonephritis associated with sle-induced lupus in mice [57]. |
| PubMedID- 25972766 | Previous studies support a protective role for both lxrs and ppar-γ in sle: lxr-α/β and ppar-γ ko mice accumulate acs in spleens, produce anti-nuclear autoantibodies and develop lupus-like syndrome with glomerulonephritis [20,29]. |
| PubMedID- 20195879 | Mycophenolate mofetil (mmf) has recently been introduced as an immunosuppressive agent for the treatment of glomerulonephritis with systemic lupus erythematosus (sle) and the data have been encouraging. |
| PubMedID- 23382559 | Mice that overexpress tlr7 develop a lupus-like disease with autoantibodies and glomerulonephritis and early death. |
| PubMedID- 21712172 | In the 78 males and 117 females (age 57+/-16 years) the indications were as follows: 47% anti-cytoplasmic antibody-associated vasculitis, 4% anti-glomerular basement membrane disease, 3% rapidly progressing immunocomplex glomerulonephritis, 11% severe complications of systemic lupus erythematosus, 1% treatment resistant focal segmental glomerular sclerosis, 5% hemolytic uremic syndrome, 13% complications of multiple myeloma, 4% hellp syndrome, 10% neurological diseases, and 2% other abnormalities. |
| PubMedID- 23320601 | The indications for plasma exchange was as follows: lupus nephritis with crescentic glomerulonephritis, fibrinoid necrosis and thrombotic microangiopathy in renal pathological changes, severe extra-renal involvement, such as central nervous system injury, hematological abnormalities, cardiovascular diseases, catastrophic antiphospholipid antibody syndrome and so on [14]. |
| PubMedID- 22102086 | Fibrillary glomerulonephritis in a patient with systemic lupus erythematosus: a rare association. |
| PubMedID- 21162701 | Several studies point to higher creatinine, low complement levels, thrombocytopenia, anemia, hypertension, and proliferative glomerulonephritis as predictors of esrd in lupus nephritis within multi-ethnic cohorts. |
| PubMedID- 20132967 | Proliferative glomerulonephritis in lupus patients with human immunodeficiency virus infection: a difficult clinical challenge. |
| PubMedID- 22249649 | Furthermore, immune complex glomerulonephritis with features resembling lupus nephritis has been described in hiv-positive patients. |
| PubMedID- 21400484 | Objective: published criteria on the degree of proteinuria increase that defines a proteinuric flare in systemic lupus erythematosus (sle) with glomerulonephritis (gn) vary widely, likely because they are not evidence based, but are largely based on expert opinion. |
| PubMedID- 21420703 | Methods: we report an observation of a patient with lupus complicated by glomerulonephritis and ih. |
| PubMedID- 23754328 | Suppression of glomerulonephritis in lupus-prone nzb x nzw mice by rn486, a selective inhibitor of bruton's tyrosine kinase. |
| PubMedID- 26558120 | Pauci-immune necrotizing and crescentic glomerulonephritis with membranous lupus nephritis, fifteen years after initial diagnosis of secondary membranous nephropathy. |
| PubMedID- 25864802 | Our results show that tpc attenuated the development of glomerulonephritis in lupus prone mice, in particular, it ameliorated proteinuria (p < 0.02), and reduced immunoglobulin deposition in the kidney mesangium. |
| PubMedID- 24604053 | All subjects suffering from any inherited or acquired diseases leading to albuminuria like glomerulonephritis, glomerular disease of diabetes mellitus, systemic lupus erythematosus, amyloidosis, hypertension, infectious diseases like hiv, hepatitis, syphilis, malaria, severe mental illness or dementia, history of drug intake liable to cause albuminuria were excluded from the study. |
| PubMedID- 23481367 | Recurrent hiv-associated immune complex glomerulonephritis with lupus-like features after kidney transplantation. |
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