PedAM
Pediatric Disease Annotations & Medicines
| Disease | lung cancer |
| Phenotype | C0686377|cns metastasis |
| Sentences | 1 |
| PubMedID- 26491347 | Xu et al and zhang et al recently reported that egfr mutation-positive lung cancer patients with cns metastasis were successfully treated with either erlotinib or icotinib singly or in combination with surgery/irradiation.8,9 although we cannot obtain the evidence of egfr mutation directly from metastatic spinal cord tumor of our reported patient, we chose a second administration of erlotinib instead of resection or continued chemotherapy for the treatment of her metastasis considering that the first administration of tki was effective and surgery and radiotherapy were not suitable for spinal cord metastasis of lung cancer; consistent with recent reports,8,9 we observed that paraspinal tumor disappeared and tumors in both lungs shrank significantly in our case with final outcome defined as pr. |
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