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PedAM

Pediatric Disease Annotations & Medicines




Disease lung cancer
Phenotype C0152013|lung adenocarcinoma
Sentences 15
PubMedID- 25396679 This study validates the ccp score and the prognostic score as independent predictors of lung cancer death in patients with early stage lung adenocarcinoma treated with surgery alone.
PubMedID- 20217555 To identify and characterize novel lung adenocarcinoma genes associated with lung cancer progression, we created a bioinformatics-based approach that focuses on human cell-cycle-regulated genes that have evolved only in higher organisms but not in lower eukaryotic cells.
PubMedID- 24113011 Compared with lung adenocarcinoma, treatment of squamous cell lung cancer (scc) has been far behind.
PubMedID- 23645403 lung cancer, including lung adenocarcinoma, is a heterogeneous disease, which evolves from molecular alterations in the airway epithelium.
PubMedID- 22966225 In one study, mice with egfr- and k-ras-driven lung adenocarcinomas, a model of platinum-resistant lung cancer, were treated with carboplatin, rosi, or both.
PubMedID- 26434887 Conclusions: this study provides new insight into the experiences of lung cancer patients y with newly diagnosed lung adenocarcinoma stage 4.
PubMedID- 21729650 Gefitinib as first-line treatment in elderly epidermal growth factor receptor-mutated patients with advanced lung adenocarcinoma: results of a nagano lung cancer research group study.
PubMedID- 25963978 In the past decade, lung adenocarcinoma, a subtype of non-small cell lung cancer (nsclc), has become the most common histological type among all lung cancers diagnosed.
PubMedID- 25035393 Fgfr2 and other fgfr kinase family gene alterations have been found in both lung squamous cell carcinoma and lung adenocarcinoma, although mouse models of fgfr-driven lung cancers have not been reported.
PubMedID- 23443124 Study subjects included 99 lung cancer patients (65 with lung adenocarcinoma, 29 with lung squamous cell carcinoma, and 5 with other carcinomas) who were after surgical treatment but not receiving radiotherapy and chemotherapy and were included in previous studies that investigated the genetic polymorphisms of dna repair proteins and metabolic enzymes [7,9,25].
PubMedID- 24885564 Background: although many of the recently approved genomically targeted therapies have improved outcomes for patients in non-small-cell lung cancer (nsclc) with lung adenocarcinoma, little is known about the genomic alterations that drive lung squamous cell cancer (scc) and development of effective targeted therapies in lung scc is a promising area to be further investigated.
PubMedID- 24048333 In this report, we assess the utility of a predefined mrna expression signature of cell-cycle progression genes (ccp score) to define 5-year risk of lung cancer-related death in patients with early stage lung adenocarcinoma.
PubMedID- 22461368 Objectives: to investigate the contribution of activated protein c (apc) and its receptor (endothelial protein c receptor [epcr]) in animal models of lung cancer metastasis and in patients with lung adenocarcinoma.
PubMedID- 23529818 Purpose: to discover common metastasis-related and prognostic markers in lung squamous carcinoma (lsc) and lung adenocarcinoma (adc), two forms of non-small cell lung cancer (nsclc).
PubMedID- 24163749 Although chemotherapeutic advances have recently been heralded in lung adenocarcinomas, such success with small-cell lung cancer (sclc) has been ominously absent.

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