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PedAM

Pediatric Disease Annotations & Medicines




Disease liver failure, acute
Phenotype C1527311|brain edema
Sentences 8
PubMedID- 20201130 Subtle bbb alterations in brain edema associated with acute liver failure.
PubMedID- 24925263 acute liver failure (alf) can lead to brain edema, cerebral hyperperfusion and intracranial hypertension.
PubMedID- 23006457 Blocking this pathway with the use of non-steroidal anti-inflammatory drugs (nsaid) such as indomethacin has been shown to improve intracranial hypertension and lower brain edema in patients with acute liver failure.
PubMedID- 26043908 In the last decade, our group was inspired by the lack of neuroprotective treatments and by the use of hypothermia after tv/fv cardiac arrest to explore the effectiveness of hypothermia in other clinical settings, such as cardiac arrest due to non-shockable rhythms, acute liver failure with brain edema, refractory intracranial hypertension (rih) or full neuroprotection intended for acute brain injuries.
PubMedID- 22321890 Objective: to investigate the expression of aquaporin-4 (aqp4) during brain edema in rats with thioacetamide-induced acute liver failure and encephalopathy.
PubMedID- 22285152 Mechanisms by which glutamine contributes to astrocyte swelling/brain edema associated with acute liver failure (alf) will also be described.
PubMedID- 24429815 Hyperammonemia, leads to cellular brain edema in humans with acute liver failure.
PubMedID- 23532086 Blood–brain barrier (bbb) dysfunction results in increased bbb permeability and subsequent brain edema1 in patients with acute liver failure (alf).

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