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PedAM

Pediatric Disease Annotations & Medicines




Disease liver disease
Phenotype C0023890|liver cirrhosis
Sentences 25
PubMedID- 22879914 These dogs therefore could serve as model for wilson’s disease and in general for chronic liver disease leading to end-stage liver cirrhosis.
PubMedID- 26504859 In addition it was found that zn levels depend on the severity of liver disease; thus, in patients with decompensated liver cirrhosis, zn concentrations are reduced by up to 75%, this is explained by changes in the protein and amino acid metabolism and by disturbances in intestinal resorption and hepatic zn extraction [33].
PubMedID- 25710025 Irrespective of the etiology, persisting liver fibrogenesis is widely recognized as the major driving force for the progression of any form of chronic liver disease (cld) ultimately leading to liver cirrhosis and hepatic failure [2–5].
PubMedID- 22745742 Hepatitis c virus (hcv) is a major cause for chronic liver disease leading to liver cirrhosis and hepatocellular carcinoma (hcc) [1].
PubMedID- 24030843 liver cirrhosis is the end-stage of long-standing chronic liver diseases.
PubMedID- 25175670 Case presentation: a 76-year-old caucasian man with liver cirrhosis due to non-alcoholic fatty liver disease, and type-2 diabetes was cognitively impaired and had reduced vigilance presumably caused by hepatic encephalopathy and/or alzheimer dementia.
PubMedID- 26247932 Hepatitis b virus (hbv) attacks the liver and can cause both acute as well as chronic liver diseases which might lead to liver cirrhosis and hepatocellular carcinoma.
PubMedID- 22359269 The present study aimed to investigate the biological actions of tricin on hepatic stellate cells (hscs) in vitro, exploring its potential as a treatment of liver fibrosis, since hsc proliferation is closely related to the progression of hepatic fibrogenesis in chronic liver diseases leading to irreversible liver cirrhosis and hepatocellular carcinoma.
PubMedID- 24281095 Hepatitis b and c viral infection is the most common underlying cause of chronic liver disease leading to liver cirrhosis, and aflatoxin b1 and alcohol are also well-known risk factors.
PubMedID- 23337976 Hepatocellular carcinoma (hcc) is one of the most common malignant tumors worldwide and most hcc arises from chronic liver disease, which is associated with liver cirrhosis.
PubMedID- 25232447 In fact, postpartum immune restoration can exacerbate hepatic inflammation, thereby worsening the liver disease, particularly in patients with liver cirrhosis.
PubMedID- 24901158 Background/aims: liver cirrhosis is the end-stage of various liver diseases, which has a poor prognosis and determined by deterioration of hepatic functional capacity and consecutive development of hepatic complications.
PubMedID- 21852972 The associations with hepatocellular carcinoma (pon1) and cholangiocellular carcinoma (pon3) also seem to be plausible as paraoxonases have a protective effect against oxidative stress, which plays an important role in chronic liver diseases leading to liver cirrhosis and the development of carcinomas (camps et al., 2009).
PubMedID- 26447841 [1, 2] more than 80% of hcc arise in a background of chronic liver disease with liver cirrhosis caused by chronic hepatitis b or c virus infection, alcohol abuse or obesity with non-alcoholic fatty liver disease.
PubMedID- 24845365 Background: hepatitis c virus (hcv) is the causative agent of chronic liver diseases, which usually lead to liver fibrosis, liver cirrhosis, and hepatocellular carcinoma (hcc).
PubMedID- 22039521 In most cases, hcv infection progresses to chronic liver disease, which can lead to liver cirrhosis and hepatocarcinoma [1].
PubMedID- 26494212 Hcc is a major cause of death in chronic liver diseases, especially in patients with liver cirrhosis.
PubMedID- 23178709 Background & aims: autoimmune hepatitis is a chronic inflammatory liver disease that leads to liver cirrhosis and corresponding complications, if left untreated.
PubMedID- 22204909 Hepatitis c virus (hcv) infection is a main cause of chronic liver disease, leading to liver cirrhosis and hepatocellular carcinoma (hcc).
PubMedID- 22500261 (3) chronic liver disease: patients diagnosed with liver cirrhosis by physicians with or without radiological confirmation, and patients diagnosed with chronic viral hepatitis on the basis of laboratory tests for the hepatitis a, b, and c viruses were classified into two groups; those with severe liver disease (such as liver cirrhosis with child-pugh class b, c) and those with mild liver disease (such as chronic viral hepatitis carrier, liver cirrhosis with child-pugh class a).
PubMedID- 25588648 According to the world health organization (who), about 3 % of the world’s population has been infected with this virus and nearly 80 % of the infected individuals develop chronic liver disease, leading to liver cirrhosis and, in some cases, to hepatocellular carcinoma (who 2014).
PubMedID- 22967278 liver cirrhosis, the end-stage of various liver diseases, has a poor prognosis, which is determined by deterioration of hepatic functional capacity and consecutive development of hepatic complications.
PubMedID- 24367208 It is intriguing that all chronic liver diseases eventually lead to liver cirrhosis and the sequence of steatosis, steatohepatitis and fibrosis/cirrhosis is generally accepted as causative.
PubMedID- 24019010 It can cause chronic liver disease and lead to liver cirrhosis and cancer [1].
PubMedID- 22645408 Exclusion criteria: hcv-infected patients treated with interferon α in the past six months or less, liver cirrhosis, other types of hepatitis or liver disease of different etiology, other infectious diseases, overt cardiovascular disease (based on documented history and ecg examination), endocrine diseases, lung disease, renal dysfunction (serum creatinine level >2.0 mg/dl), presence or history of neoplastic diseases, pregnant or postpartum women, and present or past history of alcohol or drug abuse.

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