PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | C0023890|cirrhosis |
| Sentences | 175 |
| PubMedID- 23369794 | Cholangiopathies frequently lead to biliary fibrosis and cirrhosis with the complications of end-stage liver disease [1–6]. |
| PubMedID- 21910861 | The above three patients had atypical forms of chronic liver disease that lead to decompensated advanced cirrhosis in two of them. |
| PubMedID- 21619386 | Conclusions: presence or absence of cirrhosis in patients with silent liver disease can be established by doppler ultrasound with high diagnostic accuracy. |
| PubMedID- 23374914 | Around the world, infection by the hepatitis c virus (hcv) causes acute and chronic liver disease and may lead to cirrhosis, liver failure and/or hepatocellular carcinoma. |
| PubMedID- 20496758 | Conclusions: real-time tissue elastography is a useful method for the diagnosis of significant fibrosis and cirrhosis in patients with chronic liver diseases. |
| PubMedID- 22648736 | cirrhosis is a form of end-stage liver disease that is the culmination of a number of chronic liver disorders. |
| PubMedID- 21970718 | After a sub-clinical phase, greater than 80% of patients progress to persistent hcv infection, the leading cause of chronic liver disease associated with cirrhosis and hepatocellular carcinoma [1,2]. |
| PubMedID- 20399524 | Excess weight is an independent risk factor for steatosis, acute alcoholic hepatitis (aah), and cirrhosis in patients with alcoholic liver disease (ald). |
| PubMedID- 24159587 | The major reasons for the increased incidence of hcc in the us are the increasing prevalence of chronic hcv infection, increased immigration from high-incidence countries in asia and africa, and the increase in the number of individuals with cirrhosis due to obesity-related fatty liver disease. |
| PubMedID- 20556834 | The patients were affected by chronic liver diseases with cirrhosis which was proven histologically (n = 58); by chronic active hepatitis c (n = 4), chronic active hepatitis b (n = 2), and chronic persistent hepatitis c (n = 6). |
| PubMedID- 23418453 | Approximately 170 million people are chronically infected with hcv, and some develop progressive liver disease which may lead to cirrhosis, hepatocellular carcinoma and death [2]. |
| PubMedID- 21957486 | Nafld-related cirrhosis can lead to end-stage liver disease and hepatocellular carcinoma (hcc). |
| PubMedID- 24796378 | Aim: liver fibrosis occurs as a result of several chronic liver diseases and leads to portal hypertension, cirrhosis and liver failure, often requiring liver transplantation. |
| PubMedID- 23936497 | Successful antiviral treatment in patients with advanced cirrhosis may halt progression of liver disease or prevent hcv re-infection of the liver graft in those awaiting liver transplantation [22]. |
| PubMedID- 24763757 | The relationship between symptomatic high risk for osas and liver damage seemed also independent of advanced liver disease, as patients with decompensated cirrhosis were excluded from the study, and the association between high risk for osas with sleepiness and steatosis grade and fibrosis stage >1 was maintained even after exclusion of patients with compensated cirrhosis. |
| PubMedID- 22712870 | Lmwh at 0.7 u anti-xa ml completely inhibited tg in 9/30 cirrhosis patients with more advanced liver disease (child pugh b and c), whereas complete tg abolition was seen in only 1/10 controls. |
| PubMedID- 22235351 | Older age, male sex, cirrhosis and sustained activity of liver disease are important predicators for hcc[5]. |
| PubMedID- 22500261 | (3) chronic liver disease: patients diagnosed with liver cirrhosis by physicians with or without radiological confirmation, and patients diagnosed with chronic viral hepatitis on the basis of laboratory tests for the hepatitis a, b, and c viruses were classified into two groups; those with severe liver disease (such as liver cirrhosis with child-pugh class b, c) and those with mild liver disease (such as chronic viral hepatitis carrier, liver cirrhosis with child-pugh class a). |
| PubMedID- 24076416 | However, cirrhosis increases the risk of death and liver disease. |
| PubMedID- 24581591 | For the diagnosis of the so-called idiopathic ncph, it is essential to rule out chronic liver diseases associated with progression to cirrhosis as viral hepatitis b and c, alcoholic and non-alcoholic fatty liver, autoimmune disease, hereditary hemochromatosis, wilson's disease as well as primary biliary cirrhosis and primary sclerosing cholagitis. |
| PubMedID- 25848466 | Several conditions, especially chronic liver diseases, can lead to cirrhosis in children and adolescents. |
| PubMedID- 26494212 | As hcc is closely related to liver cirrhosis, the monitoring of chronic liver diseases is of considerable importance. |
| PubMedID- 24046790 | Egy-score predicts severe hepatic fibrosis and cirrhosis in egyptians with chronic liver diseases: a pilot study. |
| PubMedID- 24367229 | The majority of patients (72%) had decompensated liver cirrhosis which was due to alcoholic liver disease except for one case with hepatitis virus c infection and α1-antitrypsin deficiency. |
| PubMedID- 21633726 | Transient elastography is a noninvasive method for detection of cirrhosis in patients with chronic liver disease by measuring the liver stiffness. |
| PubMedID- 25462064 | While alcohol is necessary for the development of ald, only 20-30% of alcoholics develop alcoholic steatohepatitis (ash) with progressive liver disease leading to cirrhosis and liver failure (ald). |
| PubMedID- 21520174 | Conclusion: this study provides the first experimental evidence that telomerase gene mutations are present in patients developing cirrhosis as a consequence of chronic liver disease. |
| PubMedID- 21687605 | Among patients with cirrhosis, the severity of liver disease were as follows: child pugh a n = 11, child pugh b n = 15, and child pugh c n = 21. stages of fibrosis in noncirrhotic patients were as follows: stage 1 n = 10, stage 2 n = 7, stage 3 n = 3, and stage 4 n = 1 (table 1). |
| PubMedID- 24129500 | Purposes: hepatic lipid overloading induces lipotoxicity which can cause hepatocyte damage, fibrosis, and eventually progress to cirrhosis, which is associated with nonalcoholic fatty liver disease. |
| PubMedID- 23610585 | Inefficient local immunity was demonstrated in liver disease; patients with cirrhosis in particular. |
| PubMedID- 25896480 | Patients with hcv are accompanied by chronic liver disease, which can lead to fibrosis, cirrhosis, and an increased risk of complications including ascites and hepatocellular carcinoma. |
| PubMedID- 23880821 | In addition, we lacked assessment of underlying liver disease, although men with cirrhosis were excluded from the cohort at baseline and associations did not vary over 24 years of follow-up. |
| PubMedID- 21810745 | Among the systemic diseases that allocated patients to asa score >2, chronic liver disease including cirrhosis was significantly more frequent in patients with treatment failure than in those with remission (8 of 21 vs 9 of 77; p = .01). |
| PubMedID- 24475094 | Fibrosis is a consequence of chronic liver disease and may lead to cirrhosis and liver failure. |
| PubMedID- 25710025 | Irrespective of the etiology, persisting liver fibrogenesis is widely recognized as the major driving force for the progression of any form of chronic liver disease (cld) ultimately leading to liver cirrhosis and hepatic failure [2–5]. |
| PubMedID- 22809449 | First, since the progression from fibrosis to cirrhosis, the end-point of chronic liver diseases, is characterized by a chronic and persistent inflammatory reaction [35.36], we suggest that such chronic inflammation, in addition to stimulating the local release of angiogenic factors by hepatic stellate cells and sinusoidal endothelial cells [35,36], may at the same time suppress the mobilization of epcs from bone marrow into the circulation. |
| PubMedID- 23546360 | In patients whom the liver is the most impaired organ, the liver disease can present with recurrent hepatitis, cirrhosis, or liver failure. |
| PubMedID- 24106597 | Liver fibrosis and its end-stage disease, cirrhosis, are outcomes of many chronic liver diseases, such as viral hepatitis and of alcohol consumption and drug abuse (27). |
| PubMedID- 26504859 | In addition it was found that zn levels depend on the severity of liver disease; thus, in patients with decompensated liver cirrhosis, zn concentrations are reduced by up to 75%, this is explained by changes in the protein and amino acid metabolism and by disturbances in intestinal resorption and hepatic zn extraction [33]. |
| PubMedID- 22039521 | In most cases, hcv infection progresses to chronic liver disease, which can lead to liver cirrhosis and hepatocarcinoma [1]. |
| PubMedID- 25263751 | Patients with compensated liver disease, including cirrhosis, were eligible for inclusion in this study. |
| PubMedID- 26556483 | Through subgroup meta-analysis, we identified significant hepatoprotective effects of coffee consumption on hepatic fibrosis and cirrhosis in patients with alcoholic liver disease and chronic hcv infection, which mainly contribute to cld in western countries. |
| PubMedID- 26099526 | Background & aims: alcoholic steatohepatitis (ash) is the progressive form of alcoholic liver disease and may lead to cirrhosis and hepatocellular carcinoma. |
| PubMedID- 25629773 | Hbv-aclf is a severe situation occurred under existing chronic liver disease with or without cirrhosis, which represents a complex situation which is different from cirrhosis [1, 6]. |
| PubMedID- 20716942 | In addition, chronic alcoholic liver disease (ald), with or without cirrhosis, increases risk for hepatocellular carcinoma (hcc). |
| PubMedID- 25887140 | The estimated recruitment period is 24 months, and recruitment started in february 2014.table 1inclusion and exclusion criteriaainclusion criteriaexclusion criteriaage ≥18 years.age <18 years.written informed consent to participate in the clinical trial and written informed consent for genetic testing.absent written informed consent to participate in the clinical trial or for genetic testing.patients have to be able to understand and follow instructions and to be willing to attend all study visits (compliance).patients unable to understand the meaning of the clinical trial and the consequences of study participation.presence or history of ascites in case of advanced liver disease compatible with cirrhosis (liver biopsy not required).patients unable to understand or follow instructions or not willing to attend all study visits.diagnostic paracentesis to exclude sbp within 10 days before the baseline visit. |
| PubMedID- 25651500 | Liver stiffness measurement (lsm) using te (fibroscan®) is accurate in identifying significant fibrosis, and in particular cirrhosis, in a number of liver diseases (5). |
| PubMedID- 25678995 | A diagnostic model for cirrhosis in patients with non-alcoholic fatty liver disease: an artificial neural network approach. |
| PubMedID- 24030843 | Liver cirrhosis is the end-stage of long-standing chronic liver diseases. |
| PubMedID- 23202682 | This study has found that death from chronic liver disease, including cirrhosis, on the county level in north carolina’s 100 counties correlates with on-road concentrations of manganese. |