PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Phenotype | C0008370|cholestasis |
| Sentences | 8 |
| PubMedID- 26006201 | Background/aims: there is little data concerning the incidence of alpha-1-antitrypsin"(aat) deficiency, the most common genetic cause of liver disease, among children with neonatal cholestasis in iran. |
| PubMedID- 23755201 | cholestasis is associated with many liver diseases, and bile duct ligation (bdl) has been used in an animal model of chronic liver injury because it duplicates the hepatocyte damage, hsc activation, and liver fibrosis observed in human liver diseases. |
| PubMedID- 19447449 | [fatal acute hepatitis and cholestasis associated with liver disease]. |
| PubMedID- 23240869 | Background: biliary obstruction and cholestasis are serious complications of many liver diseases. |
| PubMedID- 23166903 | Objectives: to report the clinical efficacy and safety of mars therapy for intractable pruritus in cholestasis patients with stable chronic liver disease, characterizing the impact of mars on cytokine levels and on the transcriptome in the blood compartment. |
| PubMedID- 20425482 | New evidence exists that although liver transplantation is curative for patients with end-stage liver disease owing to cholestasis, some patients may develop recurrence of cholestasis because of the emergence of autoantibodies that disrupt canalicular function in the new graft. |
| PubMedID- 26366057 | Among the three aspects, cholestasis associated with liver diseases is most commonly featured by the enhancement of reactive oxygen species (ros) and reduction of antioxidant systems such as glutathione (gsh), which finally results in oxidative stress and directly induces the apoptosis of hepatocytes. |
| PubMedID- 19949348 | Alagille syndrome is a multisystem disorder in which progressive liver disease with persistent cholestasis and dramatic pruritus often warrant consideration for liver transplantation. |
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