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PedAM

Pediatric Disease Annotations & Medicines




Disease liver disease
Phenotype C0005940|bone disease
Sentences 5
PubMedID- 21971374 Background and aims: metabolic bone disease is common in patients with chronic liver disease.
PubMedID- 23269891 However, both decreased 25-hydroxylation of vitamin d in the liver and a defect of kupffer cell-mediated cleavage of pth from hepatic dysfunction can contribute to the higher prevalence of metabolic bone diseases in patients with chronic liver disease compared with those without liver disease [3].
PubMedID- 24628047 Vitamin d deficiency, parathyroid hormone levels, and bone disease among patients with end-stage liver disease and normal serum creatinine awaiting liver transplantation.
PubMedID- 21772972 Similar alarming observation is the association between human bone diseases with liver diseases, like viral liver cirrhosis is a risk factor for increased loss of minerals from bone [4, 5].
PubMedID- 25061487 The term ‘hepatic osteodystrophy’ was first introduced in 1960 and refers to a metabolic bone disease (mbd) in patients with chronic liver diseases.

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