PedAM
Pediatric Disease Annotations & Medicines
| Disease | leukostasis |
| Phenotype | C0011884|diabetic retinopathy |
| Sentences | 2 |
| PubMedID- 24300231 | Have shown that tnfα could be a therapeutic target for the prevention of the progressive blood-retinal barrier breakdown, retinal leukostasis, and apoptosis associated with diabetic retinopathy [112]. |
| PubMedID- 22132311 | Evidence that leukostasis in diabetic retinopathy is linked to oxidant stress and other downstream mediators comes from the observation that alpha-lipoic acid abrogates increases in leukocyte adhesion while other mechanisms, linked to pkc pathways, are responsible for hemodynamic alterations that occur concomitantly with leukostasis [30]. |
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