PedAM
Pediatric Disease Annotations & Medicines
| Disease | leukoplakia |
| Phenotype | C0026640|oral cancer |
| Sentences | 5 |
| PubMedID- 25552924 | Studies have revealed that bmi-1 expression is associated with the development of oral cancer in patients with oral leukoplakia (lp) 14, oral erythroplakia 11, and oral lichen planus 15. in clinical specimens of hnscc, many researchers have found that the overexpression of bmi-1 correlates with poor overall survival 13,16,31. similarly, we also found that the expression of bmi1 was higher in tscc and correlated with a poor overall survival and was also associated with lymph node metastasis and clinical stage. |
| PubMedID- 21743397 | Results: salivary il-1beta and il-6 were significantly higher in oral cancer patients than in patients with leukoplakia and control group (p<0.05). |
| PubMedID- 23473850 | Objectives: recent studies have identified podoplanin, a mucin-type transmembrane glycoprotein, as a biomarker for oral cancer risk in patients with oral leukoplakia (opl). |
| PubMedID- 22514665 | oral cancer development in patients with leukoplakia--clinicopathological factors affecting outcome. |
| PubMedID- 24328950 | Precancerous lesions, such as leukoplakia, may lead to oral cancers, but the majority of precancerous lesions never undergo malignant transformation. |
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